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The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemia.
Magliulo D, Simoni M, Caserta C, Fracassi C, Belluschi S, Giannetti K, Pini R, Zapparoli E, Beretta S, Uggè M, Draghi E, Rossari F, Coltella N, Tresoldi C, Morelli MJ, Di Micco R, Gentner B, Vago L, Bernardi R. Magliulo D, et al. Among authors: giannetti k. EMBO Mol Med. 2023 Nov 8;15(11):e17810. doi: 10.15252/emmm.202317810. Epub 2023 Oct 9. EMBO Mol Med. 2023. PMID: 37807875 Free PMC article.
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse.
Gambacorta V, Beretta S, Ciccimarra M, Zito L, Giannetti K, Andrisani A, Gnani D, Zanotti L, Oliveira G, Carrabba MG, Cittaro D, Merelli I, Ciceri F, Di Micco R, Vago L. Gambacorta V, et al. Among authors: giannetti k. Cancer Discov. 2022 Jun 2;12(6):1449-1461. doi: 10.1158/2159-8290.CD-21-0980. Cancer Discov. 2022. PMID: 35255120 Free PMC article.
One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Kyrodimos E, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Vatsellas G, Petty R, Thanos D, Demaria M, Evangelou K, Di Micco R, Gorgoulis VG. Magkouta S, et al. Among authors: giannetti k. STAR Protoc. 2024 Mar 15;5(1):102929. doi: 10.1016/j.xpro.2024.102929. Epub 2024 Mar 8. STAR Protoc. 2024. PMID: 38460134 Free PMC article.
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis.
Biavasco R, Lettera E, Giannetti K, Gilioli D, Beretta S, Conti A, Scala S, Cesana D, Gallina P, Norelli M, Basso-Ricci L, Bondanza A, Cavalli G, Ponzoni M, Dagna L, Doglioni C, Aiuti A, Merelli I, Di Micco R, Montini E. Biavasco R, et al. Among authors: giannetti k. Nat Commun. 2021 Jul 27;12(1):4559. doi: 10.1038/s41467-021-24876-1. Nat Commun. 2021. PMID: 34315896 Free PMC article.