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Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function.
Grevendonk L, Connell NJ, McCrum C, Fealy CE, Bilet L, Bruls YMH, Mevenkamp J, Schrauwen-Hinderling VB, Jörgensen JA, Moonen-Kornips E, Schaart G, Havekes B, de Vogel-van den Bosch J, Bragt MCE, Meijer K, Schrauwen P, Hoeks J. Grevendonk L, et al. Among authors: moonen kornips e. Nat Commun. 2021 Aug 6;12(1):4773. doi: 10.1038/s41467-021-24956-2. Nat Commun. 2021. PMID: 34362885 Free PMC article.
Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial.
Veelen A, Andriessen C, Op den Kamp Y, Erazo-Tapia E, de Ligt M, Mevenkamp J, Jörgensen JA, Moonen-Kornips E, Schaart G, Esterline R, Havekes B, Oscarsson J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P. Veelen A, et al. Among authors: moonen kornips e. Metabolism. 2023 Mar;140:155396. doi: 10.1016/j.metabol.2022.155396. Epub 2022 Dec 30. Metabolism. 2023. PMID: 36592688 Free article. Clinical Trial.
Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance.
Harmsen JF, Kotte M, Habets I, Bosschee F, Frenken K, Jorgensen JA, de Kam S, Moonen-Kornips E, Cissen J, Doligkeit D, van de Weijer T, Erazo-Tapia E, Buitinga M, Hoeks J, Schrauwen P. Harmsen JF, et al. Among authors: moonen kornips e. J Physiol. 2023 Dec 5. doi: 10.1113/JP285523. Online ahead of print. J Physiol. 2023. PMID: 38051503
Future studies should investigate alternative exercise strategies or types of interventions (e.g. diet or drugs aiming at improving insulin sensitivity) for their capacity to reinforce diurnal variation in substrate metabolism and mitochondrial respiration. ...
Future studies should investigate alternative exercise strategies or types of interventions (e.g. diet or drugs aiming at improving i …
Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment.
Schrauwen P, Mensink M, Schaart G, Moonen-Kornips E, Sels JP, Blaak EE, Russell AP, Hesselink MK. Schrauwen P, et al. Among authors: moonen kornips e. J Clin Endocrinol Metab. 2006 Apr;91(4):1520-5. doi: 10.1210/jc.2005-1572. Epub 2005 Dec 29. J Clin Endocrinol Metab. 2006. PMID: 16384852
OBJECTIVE: We compared skeletal muscle UCP3 protein levels in prediabetic subjects [i.e. impaired glucose tolerance (IGT)], diabetic patients, and healthy controls and examined whether rosiglitazone treatment was able to restore UCP3. ...
OBJECTIVE: We compared skeletal muscle UCP3 protein levels in prediabetic subjects [i.e. impaired glucose tolerance (IGT)], diabetic …