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Did you mean g schaap[Author] (131 results)?
Genome editing of polyploid crops: prospects, achievements and bottlenecks.
Schaart JG, van de Wiel CCM, Smulders MJM. Schaart JG, et al. Transgenic Res. 2021 Aug;30(4):337-351. doi: 10.1007/s11248-021-00251-0. Epub 2021 Apr 12. Transgenic Res. 2021. PMID: 33846956 Free PMC article. Review.
The efficiency of traditional breeding based on crossing and selection has been improved by using marker-assisted selection (MAS), and MAS is also being applied in polyploid crops, which helps e.g. for introgression breeding. However, methods such as random mutation breedi …
The efficiency of traditional breeding based on crossing and selection has been improved by using marker-assisted selection (MAS), and MAS i …
Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial.
Veelen A, Andriessen C, Op den Kamp Y, Erazo-Tapia E, de Ligt M, Mevenkamp J, Jörgensen JA, Moonen-Kornips E, Schaart G, Esterline R, Havekes B, Oscarsson J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P. Veelen A, et al. Among authors: schaart g. Metabolism. 2023 Mar;140:155396. doi: 10.1016/j.metabol.2022.155396. Epub 2022 Dec 30. Metabolism. 2023. PMID: 36592688 Free article. Clinical Trial.
RESULTS: Dapagliflozin treatment resulted in a urinary glucose excretion of 36 g/24-h, leading to a negative energy and fat balance. Dapagliflozin treatment resulted in a higher 24-hour and nocturnal fat oxidation (p = 0.043 and p = 0.039, respectively), and a lower 24-hou …
RESULTS: Dapagliflozin treatment resulted in a urinary glucose excretion of 36 g/24-h, leading to a negative energy and fat balance. …
Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial.
van Beek SMM, Bruls YMH, Vanweert F, Fealy CE, Connell NJ, Schaart G, Moonen-Kornips E, Jörgensen JA, Vaz FM, Smeets ETHC, Joris PJ, Gemmink A, Houtkooper RH, Hesselink MKC, Bengtsson T, Havekes B, Schrauwen P, Hoeks J. van Beek SMM, et al. Among authors: schaart g. Nat Commun. 2023 Jan 12;14(1):173. doi: 10.1038/s41467-023-35798-5. Nat Commun. 2023. PMID: 36635304 Free PMC article. Clinical Trial.
We here investigate the effects of two-weeks treatment with the beta(2)-agonist clenbuterol (40 g/day) on glucose control as well as energy- and substrate metabolism in healthy young men (age: 18-30 years, BMI: 20-25 kg/m(2)) in a randomised, placebo-controlled, double-bli …
We here investigate the effects of two-weeks treatment with the beta(2)-agonist clenbuterol (40 g/day) on glucose control as well as …
Hibernoma with metabolic impact?
Vijgen GH, Bouvy ND, Smidt M, Kooreman L, Schaart G, van Marken Lichtenbelt W. Vijgen GH, et al. Among authors: schaart g. BMJ Case Rep. 2012 Aug 21;2012:bcr2012006325. doi: 10.1136/bcr-2012-006325. BMJ Case Rep. 2012. PMID: 22914232 Free PMC article.
The development of a cisgenic apple plant.
Vanblaere T, Szankowski I, Schaart J, Schouten H, Flachowsky H, Broggini GA, Gessler C. Vanblaere T, et al. Among authors: schaart j. J Biotechnol. 2011 Jul 20;154(4):304-11. doi: 10.1016/j.jbiotec.2011.05.013. Epub 2011 Jun 1. J Biotechnol. 2011. PMID: 21663775
Cisgenesis represents a step toward a new generation of GM crops. The lack of selectable genes (e.g. antibiotic or herbicide resistance) in the final product and the fact that the inserted gene(s) derive from organisms sexually compatible with the target crop should rise l …
Cisgenesis represents a step toward a new generation of GM crops. The lack of selectable genes (e.g. antibiotic or herbicide resistan …
Muscle fiber-type distribution, fiber-type-specific damage, and the Pompe disease phenotype.
van den Berg LE, Drost MR, Schaart G, de Laat J, van Doorn PA, van der Ploeg AT, Reuser AJ. van den Berg LE, et al. Among authors: schaart g. J Inherit Metab Dis. 2013 Sep;36(5):787-94. doi: 10.1007/s10545-012-9541-7. Epub 2012 Oct 11. J Inherit Metab Dis. 2013. PMID: 23053471
Pompe patients have the same fiber-type distribution as healthy persons, but among nonclassic patients with the same GAA mutation (c.-32-13T>G), those with early onset of symptoms tend to have more type 2 muscle fibers than those with late-onset disease. ...
Pompe patients have the same fiber-type distribution as healthy persons, but among nonclassic patients with the same GAA mutation (c.-32-13T …
The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity.
Broeders EP, Nascimento EB, Havekes B, Brans B, Roumans KH, Tailleux A, Schaart G, Kouach M, Charton J, Deprez B, Bouvy ND, Mottaghy F, Staels B, van Marken Lichtenbelt WD, Schrauwen P. Broeders EP, et al. Among authors: schaart g. Cell Metab. 2015 Sep 1;22(3):418-26. doi: 10.1016/j.cmet.2015.07.002. Epub 2015 Jul 30. Cell Metab. 2015. PMID: 26235421 Free article.
In rodents, BAT can be activated by bile acids, which activate type 2 iodothyronine deiodinase (D2) in BAT via the G-coupled protein receptor TGR5, resulting in increased oxygen consumption and energy expenditure. ...
In rodents, BAT can be activated by bile acids, which activate type 2 iodothyronine deiodinase (D2) in BAT via the G-coupled protein …
Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial.
Bruls YM, de Ligt M, Lindeboom L, Phielix E, Havekes B, Schaart G, Kornips E, Wildberger JE, Hesselink MK, Muoio D, Schrauwen P, Schrauwen-Hinderling VB. Bruls YM, et al. Among authors: schaart g. EBioMedicine. 2019 Nov;49:318-330. doi: 10.1016/j.ebiom.2019.10.017. Epub 2019 Oct 31. EBioMedicine. 2019. PMID: 31676389 Free PMC article. Clinical Trial.
METHODS: Eleven IGT- volunteers followed a 36-day placebo- and L-carnitine treatment (2 g/day) in a randomised, placebo-controlled, double blind crossover design. ...
METHODS: Eleven IGT- volunteers followed a 36-day placebo- and L-carnitine treatment (2 g/day) in a randomised, placebo-controlled, d …
18 results