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maria beaver[Author]
(1 results)?
Amyloid-β Peptide Impact on Synaptic Function and Neuroepigenetic Gene Control Reveal New Therapeutic Strategies for Alzheimer's Disease.
Front Mol Neurosci. 2020 Nov 13;13:577622. doi: 10.3389/fnmol.2020.577622. eCollection 2020.
Front Mol Neurosci. 2020.
PMID: 33304239
Free PMC article.
Review.
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain.
Beaver M, Karisetty BC, Zhang H, Bhatnagar A, Armour E, Parmar V, Brown R, Xiang M, Elefant F.
Beaver M, et al.
Epigenetics. 2022 Jun-Jul;17(7):786-807. doi: 10.1080/15592294.2021.1959742. Epub 2021 Aug 9.
Epigenetics. 2022.
PMID: 34369292
Free PMC article.
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Hippocampal stimulation promotes intracellular Tip60 dynamics with concomitant genome reorganization and synaptic gene activation.
Karnay A, Karisetty BC, Beaver M, Elefant F.
Karnay A, et al. Among authors: beaver m.
Mol Cell Neurosci. 2019 Dec;101:103412. doi: 10.1016/j.mcn.2019.103412. Epub 2019 Nov 1.
Mol Cell Neurosci. 2019.
PMID: 31682915
Free PMC article.
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Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition.
Panikker P, Xu SJ, Zhang H, Sarthi J, Beaver M, Sheth A, Akhter S, Elefant F.
Panikker P, et al. Among authors: beaver m.
J Neurosci. 2018 May 9;38(19):4569-4583. doi: 10.1523/JNEUROSCI.2840-17.2018. Epub 2018 Apr 13.
J Neurosci. 2018.
PMID: 29654189
Free PMC article.
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Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Beaver M, Bhatnagar A, Panikker P, Zhang H, Snook R, Parmar V, Vijayakumar G, Betini N, Akhter S, Elefant F.
Beaver M, et al.
Sci Rep. 2020 Oct 26;10(1):18265. doi: 10.1038/s41598-020-75035-3.
Sci Rep. 2020.
PMID: 33106538
Free PMC article.
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Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration.
Zhang H, Karisetty BC, Bhatnagar A, Armour EM, Beaver M, Roach TV, Mortazavi S, Mandloi S, Elefant F.
Zhang H, et al. Among authors: beaver m.
Mol Cell Neurosci. 2020 Dec;109:103570. doi: 10.1016/j.mcn.2020.103570. Epub 2020 Nov 4.
Mol Cell Neurosci. 2020.
PMID: 33160016
Free PMC article.
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