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Fumarate hydratase as a therapeutic target in renal cancer.
Kancherla P, Daneshvar M, Sager RA, Mollapour M, Bratslavsky G. Kancherla P, et al. Expert Opin Ther Targets. 2020 Sep;24(9):923-936. doi: 10.1080/14728222.2020.1804862. Epub 2020 Oct 6. Expert Opin Ther Targets. 2020. PMID: 32744123 Review.
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect.
Woodford MR, Baker-Williams AJ, Sager RA, Backe SJ, Blanden AR, Hashmi F, Kancherla P, Gori A, Loiselle DR, Castelli M, Serapian SA, Colombo G, Haystead TA, Jensen SM, Stetler-Stevenson WG, Loh SN, Schmidt LS, Linehan WM, Bah A, Bourboulia D, Bratslavsky G, Mollapour M. Woodford MR, et al. Among authors: kancherla p. Nat Struct Mol Biol. 2021 Aug;28(8):662-670. doi: 10.1038/s41594-021-00633-2. Epub 2021 Aug 11. Nat Struct Mol Biol. 2021. PMID: 34381247 Free PMC article.
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions.
Paladino A, Woodford MR, Backe SJ, Sager RA, Kancherla P, Daneshvar MA, Chen VZ, Bourboulia D, Ahanin EF, Prodromou C, Bergamaschi G, Strada A, Cretich M, Gori A, Veronesi M, Bandiera T, Vanna R, Bratslavsky G, Serapian SA, Mollapour M, Colombo G. Paladino A, et al. Among authors: kancherla p. Chemistry. 2020 Aug 3;26(43):9459-9465. doi: 10.1002/chem.202000615. Epub 2020 Jul 8. Chemistry. 2020. PMID: 32167602 Free PMC article.