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Activation of anti-oxidant Keap1/Nrf2 pathway modulates efficacy of dihydroartemisinin-based monotherapy and combinatory therapy with ionizing radiation.
Free Radic Biol Med. 2021 May 20;168:44-54. doi: 10.1016/j.freeradbiomed.2021.03.024. Epub 2021 Mar 26.
Free Radic Biol Med. 2021.
PMID: 33775773
Loss of pro-apoptotic Bax and Bak increases resistance to dihydroartemisinin-mediated cytotoxicity in normoxia but not in hypoxia in HCT116 colorectal cancer cells.
Bader S, Wilmers J, Ontikatze T, Ritter V, Jendrossek V, Rudner J.
Bader S, et al. Among authors: wilmers j.
Free Radic Biol Med. 2021 Oct;174:157-170. doi: 10.1016/j.freeradbiomed.2021.08.012. Epub 2021 Aug 14.
Free Radic Biol Med. 2021.
PMID: 34403740
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