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Page 1
Acetyl-CoA carboxylase 2 inhibition reduces skeletal muscle bioactive lipid content and attenuates progression of type 2 diabetes in Zucker diabetic fatty rats.
Eur J Pharmacol. 2021 Nov 5;910:174451. doi: 10.1016/j.ejphar.2021.174451. Epub 2021 Aug 27.
Eur J Pharmacol. 2021.
PMID: 34454928
Discovery of peroxisome proliferator-activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line.
Tachibana K, Yuzuriha T, Tabata R, Fukuda S, Maegawa T, Takahashi R, Tanimoto K, Tsujino H, Nunomura K, Lin B, Matsuura Y, Tanaka T, Hamakubo T, Sakai J, Kodama T, Kobayashi T, Ishimoto K, Miyachi H, Doi T.
Tachibana K, et al. Among authors: tanimoto k.
J Biol Chem. 2018 Jun 29;293(26):10333-10343. doi: 10.1074/jbc.RA118.002077. Epub 2018 May 15.
J Biol Chem. 2018.
PMID: 29764933
Free PMC article.
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A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways.
Takagi H, Tanimoto K, Shimazaki A, Tonomura Y, Momosaki S, Sakamoto S, Abe K, Notoya M, Yukioka H.
Takagi H, et al. Among authors: tanimoto k.
J Pharmacol Exp Ther. 2020 Mar;372(3):256-263. doi: 10.1124/jpet.119.263590. Epub 2020 Jan 3.
J Pharmacol Exp Ther. 2020.
PMID: 31900320
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Chronic hyperinsulinemia contributes to insulin resistance under dietary restriction in association with altered lipid metabolism in Zucker diabetic fatty rats.
Morita I, Tanimoto K, Akiyama N, Naya N, Fujieda K, Iwasaki T, Yukioka H.
Morita I, et al. Among authors: tanimoto k.
Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E264-E272. doi: 10.1152/ajpendo.00342.2016. Epub 2017 Jan 31.
Am J Physiol Endocrinol Metab. 2017.
PMID: 28143857
Free article.
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