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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 2
2010 3
2011 1
2012 2
2014 1
2015 1
2016 2
2018 7
2019 4
2020 3
2021 1
2022 4
2023 2
2024 1

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32 results

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Page 1
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K. Hinohara K, et al. Among authors: kales sc. Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Cancer Cell. 2018. PMID: 30472020 Free PMC article.
Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors.
Crawford MC, Tripu DR, Barritt SA, Jing Y, Gallimore D, Kales SC, Bhanu NV, Xiong Y, Fang Y, Butler KAT, LeClair CA, Coussens NP, Simeonov A, Garcia BA, Dibble CC, Meier JL. Crawford MC, et al. Among authors: kales sc. ACS Chem Biol. 2023 Oct 20;18(10):2249-2258. doi: 10.1021/acschembio.3c00293. Epub 2023 Sep 22. ACS Chem Biol. 2023. PMID: 37737090 Free PMC article.
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.
Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP. Coussens NP, et al. Among authors: kales sc. Clin Transl Sci. 2018 Sep;11(5):461-470. doi: 10.1111/cts.12570. Epub 2018 Jul 24. Clin Transl Sci. 2018. PMID: 29877628 Free PMC article. Review.
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2.
Scoles DR, Gandelman M, Paul S, Dexheimer T, Dansithong W, Figueroa KP, Pflieger LT, Redlin S, Kales SC, Sun H, Maloney D, Damoiseaux R, Henderson MJ, Simeonov A, Jadhav A, Pulst SM. Scoles DR, et al. Among authors: kales sc. J Biol Chem. 2022 Aug;298(8):102228. doi: 10.1016/j.jbc.2022.102228. Epub 2022 Jul 2. J Biol Chem. 2022. PMID: 35787375 Free PMC article.
Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors.
Crawford MC, Tripu DR, Barritt SA, Jing Y, Gallimore D, Kales SC, Bhanu NV, Xiong Y, Fang Y, Butler KAT, LeClair CA, Coussens NP, Simeonov A, Garcia BA, Dibble CC, Meier JL. Crawford MC, et al. Among authors: kales sc. bioRxiv [Preprint]. 2023 May 16:2023.05.15.540887. doi: 10.1101/2023.05.15.540887. bioRxiv. 2023. Update in: ACS Chem Biol. 2023 Oct 20;18(10):2249-2258. doi: 10.1021/acschembio.3c00293. PMID: 37292747 Free PMC article. Updated. Preprint.
Loss of function Cbl-c mutations in solid tumors.
Daniels SR, Liyasova M, Kales SC, Nau MM, Ryan PE, Green JE, Lipkowitz S. Daniels SR, et al. Among authors: kales sc. PLoS One. 2019 Jul 1;14(7):e0219143. doi: 10.1371/journal.pone.0219143. eCollection 2019. PLoS One. 2019. PMID: 31260484 Free PMC article.
Cbl exposes its RING finger.
Kales SC, Ryan PE, Lipkowitz S. Kales SC, et al. Nat Struct Mol Biol. 2012 Feb 3;19(2):131-3. doi: 10.1038/nsmb.2241. Nat Struct Mol Biol. 2012. PMID: 22301873 Free PMC article.
32 results