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1974 1
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13 results

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Page 1
Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
Schneider-Hohendorf T, Gerdes LA, Pignolet B, Gittelman R, Ostkamp P, Rubelt F, Raposo C, Tackenberg B, Riepenhausen M, Janoschka C, Wünsch C, Bucciarelli F, Flierl-Hecht A, Beltrán E, Kümpfel T, Anslinger K, Gross CC, Chapman H, Kaplan I, Brassat D, Wekerle H, Kerschensteiner M, Klotz L, Lünemann JD, Hohlfeld R, Liblau R, Wiendl H, Schwab N. Schneider-Hohendorf T, et al. Among authors: liblau r. J Exp Med. 2022 Nov 7;219(11):e20220650. doi: 10.1084/jem.20220650. Epub 2022 Sep 1. J Exp Med. 2022. PMID: 36048016 Free PMC article.
Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy.
Seifinejad A, Ramosaj M, Shan L, Li S, Possovre ML, Pfister C, Fronczek R, Garrett-Sinha LA, Frieser D, Honda M, Arribat Y, Grepper D, Amati F, Picot M, Agnoletto A, Iseli C, Chartrel N, Liblau R, Lammers GJ, Vassalli A, Tafti M. Seifinejad A, et al. Among authors: liblau r. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2220911120. doi: 10.1073/pnas.2220911120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126681 Free PMC article.
Immunohistologic Features of Cerebral Venous Thrombosis Due to Vaccine-Induced Immune Thrombotic Thrombocytopenia.
Geeraerts T, Guilbeau-Frugier C, Garcia C, Memier V, Raposo N, Bonneville F, Gales C, Darcourt J, Voisin S, Ribes A, Piel-Julian M, Bounes F, Albucher JF, Roux FE, Izopet J, Telmon N, Olivot JM, Sié P, Bauer J, Payrastre B, Liblau RS. Geeraerts T, et al. Among authors: liblau rs. Neurol Neuroimmunol Neuroinflamm. 2023 May 26;10(4):e200127. doi: 10.1212/NXI.0000000000200127. Print 2023 Jul. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 37236806 Free PMC article.
Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell-Mediated Neuroinflammation.
Gonzalez-Fierro C, Fonte C, Dufourd E, Cazaentre V, Aydin S, Engelhardt B, Caspi RR, Xu B, Martin-Blondel G, Spicer JA, Trapani JA, Bauer J, Liblau RS, Bost C. Gonzalez-Fierro C, et al. Among authors: liblau rs. Neurol Neuroimmunol Neuroinflamm. 2023 Apr 20;10(4):e200117. doi: 10.1212/NXI.0000000000200117. Print 2023 Jul. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 37080596 Free PMC article.
Prediction of natalizumab anti-drug antibodies persistency.
Deisenhammer F, Jank M, Lauren A, Sjödin A, Ryner M, Fogdell-Hahn A, Sievers C, Lindberg R, Jensen PE, Sellebjerg F, Christodoulou L, Birchler M, Pallardy M, Auer M, Liblau R; ABIRISK consortium. Deisenhammer F, et al. Among authors: liblau r. Mult Scler. 2019 Mar;25(3):392-398. doi: 10.1177/1352458517753721. Epub 2018 Jan 16. Mult Scler. 2019. PMID: 29336205
The median trough drug level in ADA-positive samples was 0 g/mL. PK levels and ADA titres correlated strongly negatively ( r = -0.67). CONCLUSION: High baseline natalizumab ADA titres accurately predict persistency. ...
The median trough drug level in ADA-positive samples was 0 g/mL. PK levels and ADA titres correlated strongly negatively ( r = -0.67) …
NF-κB subunits RelA and c-Rel selectively control CD4+ T cell function in multiple sclerosis and cancer.
Lalle G, Lautraite R, Bouherrou K, Plaschka M, Pignata A, Voisin A, Twardowski J, Perrin-Niquet M, Stéphan P, Durget S, Tonon L, Ardin M, Degletagne C, Viari A, Belgarbi Dutron L, Davoust N, Postler TS, Zhao J, Caux C, Caramel J, Dalle S, Cassier PA, Klein U, Schmidt-Supprian M, Liblau R, Ghosh S, Grinberg-Bleyer Y. Lalle G, et al. Among authors: liblau r. J Exp Med. 2024 Jun 3;221(6):e20231348. doi: 10.1084/jem.20231348. Epub 2024 Apr 2. J Exp Med. 2024. PMID: 38563819
CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross CC, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher AR, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud DA, Loussouarn D, Parratt J, Barnett M, Buckland ME, Hardy TA, Reddel SW, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth SG, Martin-Blondel G, Wiendl H, Liblau R. Gross CC, et al. Among authors: liblau r. Nat Commun. 2019 Dec 18;10(1):5779. doi: 10.1038/s41467-019-13593-5. Nat Commun. 2019. PMID: 31852955 Free PMC article.
Combining Clinical and Genetic Data to Predict Response to Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients: A Precision Medicine Approach.
Ferrè L, Clarelli F, Pignolet B, Mascia E, Frasca M, Santoro S, Sorosina M, Bucciarelli F, Moiola L, Martinelli V, Comi G, Liblau R, Filippi M, Valentini G, Esposito F. Ferrè L, et al. Among authors: liblau r. J Pers Med. 2023 Jan 6;13(1):122. doi: 10.3390/jpm13010122. J Pers Med. 2023. PMID: 36675783 Free PMC article.
Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling.
Cope AP, Liblau RS, Yang XD, Congia M, Laudanna C, Schreiber RD, Probert L, Kollias G, McDevitt HO. Cope AP, et al. Among authors: liblau rs. J Exp Med. 1997 May 5;185(9):1573-84. doi: 10.1084/jem.185.9.1573. J Exp Med. 1997. PMID: 9151895 Free PMC article.
Furthermore, T cell responses of HNT-TCR transgenic mice also expressing the human TNF-globin transgene were markedly reduced compared to HNT-TCR single transgenic littermates, indicating that sustained p55 TNF-R signaling is sufficient to suppress T cell function in vivo. …
Furthermore, T cell responses of HNT-TCR transgenic mice also expressing the human TNF-globin transgene were markedly reduced compared to HN …
13 results