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Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis.
Dressel N, Natusch L, Munz CM, Costas Ramon S, Morcos MNF, Loff A, Hiller B, Haase C, Schulze L, Müller P, Lesche M, Dahl A, Luksch H, Rösen-Wolff A, Roers A, Behrendt R, Gerbaulet A. Dressel N, et al. Among authors: hiller b. Cancer Res. 2023 Sep 1;83(17):2858-2872. doi: 10.1158/0008-5472.CAN-22-3860. Cancer Res. 2023. PMID: 37335136
STING Signaling the enERGIC Way.
Hiller B, Hornung V. Hiller B, et al. Cell Host Microbe. 2015 Aug 12;18(2):137-9. doi: 10.1016/j.chom.2015.07.014. Cell Host Microbe. 2015. PMID: 26269948 Free article.
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
Tahk S, Vick B, Hiller B, Schmitt S, Marcinek A, Perini ED, Leutbecher A, Augsberger C, Reischer A, Tast B, Humpe A, Jeremias I, Subklewe M, Fenn NC, Hopfner KP. Tahk S, et al. Among authors: hiller b. J Hematol Oncol. 2021 Sep 27;14(1):155. doi: 10.1186/s13045-021-01163-6. J Hematol Oncol. 2021. PMID: 34579739 Free PMC article.
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Andreeva L, et al. Among authors: hiller b. Nature. 2017 Sep 21;549(7672):394-398. doi: 10.1038/nature23890. Epub 2017 Sep 13. Nature. 2017. PMID: 28902841