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An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma.
Zhou J, Simon JM, Liao C, Zhang C, Hu L, Zurlo G, Liu X, Fan C, Hepperla A, Jia L, Tcheuyap VT, Zhong H, Elias R, Ye J, Henne WM, Kapur P, Nijhawan D, Brugarolas J, Zhang Q. Zhou J, et al. Among authors: tcheuyap vt. Mol Cell. 2022 Aug 18;82(16):3030-3044.e8. doi: 10.1016/j.molcel.2022.06.003. Epub 2022 Jun 27. Mol Cell. 2022. PMID: 35764091 Free PMC article.
HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans.
Ma Y, Joyce A, Brandenburg O, Saatchi F, Stevens C, Toffessi Tcheuyap V, Christie A, Do QN, Fatunde O, Macchiaroli A, Wong SC, Woolford L, Yousuf Q, Miyata J, Carrillo D, Onabolu O, McKenzie T, Mishra A, Hardy T, He W, Li D, Ivanishev A, Zhang Q, Pedrosa I, Kapur P, Schluep T, Kanner SB, Hamilton J, Brugarolas J. Ma Y, et al. Among authors: toffessi tcheuyap v. Clin Cancer Res. 2022 Dec 15;28(24):5405-5418. doi: 10.1158/1078-0432.CCR-22-0963. Clin Cancer Res. 2022. PMID: 36190432 Free PMC article.
Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis.
Calhoon D, Sang L, Bezwada D, Kim N, Basu A, Hsu SC, Pimentel A, Brooks B, La K, Serrano AP, Cassidy DL, Cai L, Toffessi-Tcheuyap V, Margulis V, Cai F, Brugarolas J, Weiss RJ, DeBerardinis RJ, Birsoy K, Garcia-Bermudez J. Calhoon D, et al. Among authors: toffessi tcheuyap v. bioRxiv [Preprint]. 2024 May 13:2024.05.13.593939. doi: 10.1101/2024.05.13.593939. bioRxiv. 2024. PMID: 38765991 Free PMC article. Preprint.
Pancreatic tropism of metastatic renal cell carcinoma.
Singla N, Xie Z, Zhang Z, Gao M, Yousuf Q, Onabolu O, McKenzie T, Tcheuyap VT, Ma Y, Choi J, McKay R, Christie A, Torras OR, Bowman IA, Margulis V, Pedrosa I, Przybycin C, Wang T, Kapur P, Rini B, Brugarolas J. Singla N, et al. Among authors: tcheuyap vt. JCI Insight. 2020 Apr 9;5(7):e134564. doi: 10.1172/jci.insight.134564. JCI Insight. 2020. PMID: 32271170 Free PMC article.
Determinants of renal cell carcinoma invasion and metastatic competence.
Kim K, Zhou Q, Christie A, Stevens C, Ma Y, Onabolu O, Chintalapati S, Mckenzie T, Tcheuyap VT, Woolford L, Zhang H, Singla N, Parida PK, Marquez-Palencia M, Pedrosa I, Margulis V, Sagalowsky A, Xie Z, Wang T, Durinck S, Modrusan Z, Seshagiri S, Kapur P, Brugarolas J, Malladi S. Kim K, et al. Among authors: tcheuyap vt. Nat Commun. 2021 Oct 4;12(1):5760. doi: 10.1038/s41467-021-25918-4. Nat Commun. 2021. PMID: 34608135 Free PMC article.
Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.
Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S. Durinck S, et al. Among authors: toffessi tcheuyap v. Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17. Nat Genet. 2015. PMID: 25401301 Free PMC article.