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Page 1
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Nat Commun. 2023 Apr 14;14(1):2132. doi: 10.1038/s41467-023-37652-0.
Nat Commun. 2023.
PMID: 37059720
Free PMC article.
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma.
Anderson GSF, Ballester-Beltran J, Giotopoulos G, Guerrero JA, Surget S, Williamson JC, So T, Bloxham D, Aubareda A, Asby R, Walker I, Jenkinson L, Soilleux EJ, Roy JP, Teodósio A, Ficken C, Officer-Jones L, Nasser S, Skerget S, Keats JJ, Greaves P, Tai YT, Anderson KC, MacFarlane M, Thaventhiran JE, Huntly BJP, Lehner PJ, Chapman MA.
Anderson GSF, et al. Among authors: asby r.
Blood. 2022 Apr 21;139(16):2471-2482. doi: 10.1182/blood.2021015161.
Blood. 2022.
PMID: 35134130
Free PMC article.
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Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.
Gupta S, Dovey OM, Domingues AF, Cyran OW, Cash CM, Giotopoulos G, Rak J, Cooper J, Gozdecka M, Dijkhuis L, Asby RJ, Al-Jabery N, Hernandez-Hernandez V, Prabakaran S, Huntly BJ, Vassiliou GS, Pina C.
Gupta S, et al. Among authors: asby rj.
Sci Adv. 2022 Aug 5;8(31):eabn4886. doi: 10.1126/sciadv.abn4886. Epub 2022 Aug 3.
Sci Adv. 2022.
PMID: 35921412
Free PMC article.
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KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia.
Arede L, Foerner E, Wind S, Kulkarni R, Domingues AF, Giotopoulos G, Kleinwaechter S, Mollenhauer-Starkl M, Davison H, Chandru A, Asby R, Samarista R, Gupta S, Forte D, Curti A, Scheer E, Huntly BJP, Tora L, Pina C.
Arede L, et al. Among authors: asby r.
Blood Adv. 2022 Jan 11;6(1):165-180. doi: 10.1182/bloodadvances.2020002842.
Blood Adv. 2022.
PMID: 34654054
Free PMC article.
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Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer F, Giotopoulos G, Meduri E, Yun H, Mazan M, Sasca D, Gallipoli P, Marando L, Gozdecka M, Asby R, Sheppard O, Dudek M, Bullinger L, Döhner H, Dillon R, Freeman S, Ottmann O, Burnett A, Russell N, Papaemmanuil E, Hills R, Campbell P, Vassiliou GS, Huntly BJP.
Basheer F, et al. Among authors: asby r.
J Exp Med. 2019 Apr 1;216(4):966-981. doi: 10.1084/jem.20181276. Epub 2019 Mar 19.
J Exp Med. 2019.
PMID: 30890554
Free PMC article.
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Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.
Gong C, Krupka JA, Gao J, Grigoropoulos NF, Giotopoulos G, Asby R, Screen M, Usheva Z, Cucco F, Barrans S, Painter D, Zaini NBM, Haupl B, Bornelöv S, Ruiz De Los Mozos I, Meng W, Zhou P, Blain AE, Forde S, Matthews J, Khim Tan MG, Burke GAA, Sze SK, Beer P, Burton C, Campbell P, Rand V, Turner SD, Ule J, Roman E, Tooze R, Oellerich T, Huntly BJ, Turner M, Du MQ, Samarajiwa SA, Hodson DJ.
Gong C, et al. Among authors: asby r.
Mol Cell. 2021 Oct 7;81(19):4059-4075.e11. doi: 10.1016/j.molcel.2021.07.041. Epub 2021 Aug 25.
Mol Cell. 2021.
PMID: 34437837
Free article.
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