Anterior cingulate cortex involvement in subclinical social anxiety

Elizabeth R Duval; Lisa R Hale; Israel Liberzon; Rebecca Lepping; Joshua N Powell; Diane L Filion; Cary R Savage

doi:10.1016/j.pscychresns.2013.09.005

Anterior cingulate cortex involvement in subclinical social anxiety

Psychiatry Res. 2013 Dec 30;214(3):459-61. doi: 10.1016/j.pscychresns.2013.09.005. Epub 2013 Sep 27.

Authors

Elizabeth R Duval¹, Lisa R Hale, Israel Liberzon, Rebecca Lepping, Joshua N Powell, Diane L Filion, Cary R Savage

Affiliation

¹ Department of Psychiatry, University of Michigan Health System, 4250 Plymouth Road, Ann Arbor, MI 48109, USA; Department of Psychology, University of Missouri-Kansas City, Kansas City, MO, USA. Electronic address: eduval@med.umich.edu.

PMID: 24080515
DOI: 10.1016/j.pscychresns.2013.09.005

Abstract

We demonstrated differential activation in the anterior cingulate cortex (ACC) between subjects with high and low social anxiety in response to angry versus neutral faces. Activation in the ACC distinguished between facial expressions in the low, but not the high, anxious group. The ACC's role in threat processing is discussed.

Keywords: Backward masking; Faces; fMRI.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Anger
Anxiety / physiopathology*
Brain Mapping
Facial Expression
Female
Gyrus Cinguli / physiopathology*
Humans
Magnetic Resonance Imaging
Shyness*
Young Adult