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Year Number of Results
2007 1
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2020 3
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2023 2
2024 3

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15 results

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Page 1
Paradoxical activation of oncogenic signaling as a cancer treatment strategy.
Dias MH, Friskes A, Wang S, Fernandes Neto JM, van Gemert F, Mourragui S, Papagianni C, Kuiken HJ, Mainardi S, Alvarez-Villanueva D, Lieftink C, Morris B, Dekker A, van Dijk E, Wilms LHS, da Silva MS, Jansen RA, Mulero-Sanchez A, Malzer E, Vidal A, Santos C, Salazar R, Wailemann RAM, Torres TEP, De Conti G, Raaijmakers JA, Snaebjornsson P, Yuan S, Qin W, Kovach JS, Armelin HA, Te Riele H, van Oudernaarden A, Jin H, Beijersbergen RL, Villanueva A, Medema RH, Bernards R. Dias MH, et al. Among authors: kuiken hj. Cancer Discov. 2024 Mar 27. doi: 10.1158/2159-8290.CD-23-0216. Online ahead of print. Cancer Discov. 2024. PMID: 38533987
PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair.
Andronikou C, Burdova K, Dibitetto D, Lieftink C, Malzer E, Kuiken HJ, Gogola E, Ray Chaudhuri A, Beijersbergen RL, Hanzlikova H, Jonkers J, Rottenberg S. Andronikou C, et al. Among authors: kuiken hj. EMBO J. 2024 Mar;43(6):1015-1042. doi: 10.1038/s44318-024-00043-2. Epub 2024 Feb 15. EMBO J. 2024. PMID: 38360994 Free PMC article.
Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.
van der Noord VE, van der Stel W, Louwerens G, Verhoeven D, Kuiken HJ, Lieftink C, Grandits M, Ecker GF, Beijersbergen RL, Bouwman P, Le Dévédec SE, van de Water B. van der Noord VE, et al. Among authors: kuiken hj. Breast Cancer Res. 2023 May 5;25(1):51. doi: 10.1186/s13058-023-01648-x. Breast Cancer Res. 2023. PMID: 37147730 Free PMC article.
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse.
Chen M, Mainardi S, Lieftink C, Velds A, de Rink I, Yang C, Kuiken HJ, Morris B, Edwards F, Jochems F, van Tellingen O, Boeije M, Proost N, Jansen RA, Qin S, Jin H, Koen van der Mijn JC, Schepers A, Venkatesan S, Qin W, Beijersbergen RL, Wang L, Bernards R. Chen M, et al. Among authors: kuiken hj. Cell Rep Med. 2024 Mar 19;5(3):101471. doi: 10.1016/j.xcrm.2024.101471. Cell Rep Med. 2024. PMID: 38508142 Free PMC article.
Transient commensal clonal interactions can drive tumor metastasis.
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, Ince TA, Xiu J, Oberley M, Gatalica Z, Navin N, Mills GB, Bronson RT, Brugge JS. Naffar-Abu Amara S, et al. Among authors: kuiken hj. Nat Commun. 2020 Nov 16;11(1):5799. doi: 10.1038/s41467-020-19584-1. Nat Commun. 2020. PMID: 33199705 Free PMC article.
15 results