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Year Number of Results
2019 5
2020 3
2021 7
2022 4
2023 2
2024 1

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18 results

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Targeting NRF2 to treat cancer.
Sivinski J, Zhang DD, Chapman E. Sivinski J, et al. Semin Cancer Biol. 2021 Nov;76:61-73. doi: 10.1016/j.semcancer.2021.06.003. Epub 2021 Jun 5. Semin Cancer Biol. 2021. PMID: 34102289 Free PMC article. Review.
UniDecCD: Deconvolution of Charge Detection-Mass Spectrometry Data.
Kostelic MM, Zak CK, Liu Y, Chen VS, Wu Z, Sivinski J, Chapman E, Marty MT. Kostelic MM, et al. Among authors: sivinski j. Anal Chem. 2021 Nov 9;93(44):14722-14729. doi: 10.1021/acs.analchem.1c03181. Epub 2021 Oct 27. Anal Chem. 2021. PMID: 34705424 Free PMC article.
Allosteric differences dictate GroEL complementation of E. coli.
Sivinski J, Ngo D, Zerio CJ, Ambrose AJ, Watson ER, Kaneko LK, Kostelic MM, Stevens M, Ray AM, Park Y, Wu C, Marty MT, Hoang QQ, Zhang DD, Lander GC, Johnson SM, Chapman E. Sivinski J, et al. FASEB J. 2022 Mar;36(3):e22198. doi: 10.1096/fj.202101708RR. FASEB J. 2022. PMID: 35199390 Free PMC article.
Physachenolide C is a Potent, Selective BET Inhibitor.
Zerio CJ, Sivinski J, Wijeratne EMK, Xu YM, Ngo DT, Ambrose AJ, Villa-Celis L, Ghadirian N, Clarkson MW, Zhang DD, Horton NC, Gunatilaka AAL, Fromme R, Chapman E. Zerio CJ, et al. Among authors: sivinski j. J Med Chem. 2023 Jan 12;66(1):913-933. doi: 10.1021/acs.jmedchem.2c01770. Epub 2022 Dec 28. J Med Chem. 2023. PMID: 36577036
Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action.
Zerio CJ, Cunningham TA, Tulino AS, Alimusa EA, Buckley TM, Moore KT, Dodson M, Wilson NC, Ambrose AJ, Shi T, Sivinski J, Essegian DJ, Zhang DD, Schürer SC, Schatz JH, Chapman E. Zerio CJ, et al. Among authors: sivinski j. J Med Chem. 2021 Nov 11;64(21):15727-15746. doi: 10.1021/acs.jmedchem.1c01014. Epub 2021 Oct 22. J Med Chem. 2021. PMID: 34676755 Free PMC article.
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78.
Ambrose AJ, Sivinski J, Zerio CJ, Zhu X, Godek J, Kumirov VK, Coma Brujas T, Torra Garcia J, Annadurai A, Schmidlin CJ, Werner A, Shi T, Zavareh RB, Lairson L, Zhang DD, Chapman E. Ambrose AJ, et al. Among authors: sivinski j. J Med Chem. 2023 Jan 12;66(1):677-694. doi: 10.1021/acs.jmedchem.2c01631. Epub 2022 Dec 14. J Med Chem. 2023. PMID: 36516003
Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL.
Sivinski J, Ambrose AJ, Panfilenko I, Zerio CJ, Machulis JM, Mollasalehi N, Kaneko LK, Stevens M, Ray AM, Park Y, Wu C, Hoang QQ, Johnson SM, Chapman E. Sivinski J, et al. mBio. 2021 Jan 12;12(1):e02167-20. doi: 10.1128/mBio.02167-20. mBio. 2021. PMID: 33436430 Free PMC article.
A two-step resin based approach to reveal survivin-selective fluorescent probes.
Ambrose AJ, Pham NT, Sivinski J, Guimarães L, Mollasalehi N, Jimenez P, Abad MA, Jeyaprakash AA, Shave S, Costa-Lotufo LV, La Clair JJ, Auer M, Chapman E. Ambrose AJ, et al. Among authors: sivinski j. RSC Chem Biol. 2020 Nov 27;2(1):181-186. doi: 10.1039/d0cb00122h. eCollection 2021 Feb 1. RSC Chem Biol. 2020. PMID: 34458780 Free PMC article.
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins.
Ambrose AJ, Zerio CJ, Sivinski J, Zhu X, Godek J, Sanchez JL, Khanna M, Khanna R, Lairson L, Zhang DD, Chapman E. Ambrose AJ, et al. Among authors: sivinski j. Biochemistry. 2024 Feb 6;63(3):251-263. doi: 10.1021/acs.biochem.3c00531. Epub 2024 Jan 20. Biochemistry. 2024. PMID: 38243804
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs.
Stevens M, Howe C, Ray AM, Washburn A, Chitre S, Sivinski J, Park Y, Hoang QQ, Chapman E, Johnson SM. Stevens M, et al. Among authors: sivinski j. Bioorg Med Chem. 2020 Nov 15;28(22):115710. doi: 10.1016/j.bmc.2020.115710. Epub 2020 Aug 30. Bioorg Med Chem. 2020. PMID: 33007545 Free PMC article.
18 results