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The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.
Erkeland SJ, Stavast CJ, Schilperoord-Vermeulen J, Dal Collo G, Van de Werken HJG, Leon LG, Van Hoven-Beijen A, Van Zuijen I, Mueller YM, Bindels EM, De Ridder D, Kappers-Klunne MC, Van Lom K, Van der Velden VHJ, Langerak AW. Erkeland SJ, et al. Among authors: van hoven beijen a. Haematologica. 2022 Jan 1;107(1):143-153. doi: 10.3324/haematol.2020.263756. Haematologica. 2022. PMID: 33596640 Free PMC article.
The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis.
Stavast CJ, van Zuijen I, Karkoulia E, Özçelik A, van Hoven-Beijen A, Leon LG, Voerman JSA, Janssen GMC, van Veelen PA, Burocziova M, Brouwer RWW, van IJcken WFJ, Maas A, Bindels EM, van der Velden VHJ, Schliehe C, Katsikis PD, Alberich-Jorda M, Erkeland SJ. Stavast CJ, et al. Among authors: van hoven beijen a. Leukemia. 2022 Mar;36(3):687-700. doi: 10.1038/s41375-021-01461-5. Epub 2021 Nov 5. Leukemia. 2022. PMID: 34741119 Free PMC article.
Addition of β-mercaptoethanol is a prerequisite for high-quality RNA isolation using QIAsymphony technology as demonstrated by detection of molecular aberrations in hematologic malignancies.
van der Poel-van de Luytgaarde SC, Geertsma-Kleinekoort WM, Goudswaard CS, Hogenbirk-Hupkes PE, van Hoven-Beijen MA, van de Werf M, Chu IW, van Kapel J, Valk PJ. van der Poel-van de Luytgaarde SC, et al. Among authors: van hoven beijen ma. Genet Test Mol Biomarkers. 2013 Jun;17(6):475-80. doi: 10.1089/gtmb.2012.0448. Epub 2013 Apr 24. Genet Test Mol Biomarkers. 2013. PMID: 23614569