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Implications of human induced pluripotent stem cells in metabolic disorders: from drug discovery toward precision medicine.
Cota-Coronado A, Ramírez-Rodríguez PB, Padilla-Camberos E, Díaz ÉF, Flores-Fernández JM, Ávila-Gónzalez D, Diaz-Martinez NE. Cota-Coronado A, et al. Among authors: flores fernandez jm. Drug Discov Today. 2019 Jan;24(1):334-341. doi: 10.1016/j.drudis.2018.10.001. Epub 2018 Oct 4. Drug Discov Today. 2019. PMID: 30292915 Review.
Recent advances in the use of CRISPR/Cas for understanding the early development of molecular gaps in glial cells.
Barragán-Álvarez CP, Flores-Fernandez JM, Hernández-Pérez OR, Ávila-Gónzalez D, Díaz NF, Padilla-Camberos E, Dublan-García O, Gómez-Oliván LM, Diaz-Martinez NE. Barragán-Álvarez CP, et al. Among authors: flores fernandez jm. Front Cell Dev Biol. 2022 Sep 2;10:947769. doi: 10.3389/fcell.2022.947769. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36120556 Free PMC article. Review.
The genomic history of the Iberian Peninsula over the past 8000 years.
Olalde I, Mallick S, Patterson N, Rohland N, Villalba-Mouco V, Silva M, Dulias K, Edwards CJ, Gandini F, Pala M, Soares P, Ferrando-Bernal M, Adamski N, Broomandkhoshbacht N, Cheronet O, Culleton BJ, Fernandes D, Lawson AM, Mah M, Oppenheimer J, Stewardson K, Zhang Z, Jiménez Arenas JM, Toro Moyano IJ, Salazar-García DC, Castanyer P, Santos M, Tremoleda J, Lozano M, García Borja P, Fernández-Eraso J, Mujika-Alustiza JA, Barroso C, Bermúdez FJ, Viguera Mínguez E, Burch J, Coromina N, Vivó D, Cebrià A, Fullola JM, García-Puchol O, Morales JI, Oms FX, Majó T, Vergès JM, Díaz-Carvajal A, Ollich-Castanyer I, López-Cachero FJ, Silva AM, Alonso-Fernández C, Delibes de Castro G, Jiménez Echevarría J, Moreno-Márquez A, Pascual Berlanga G, Ramos-García P, Ramos-Muñoz J, Vijande Vila E, Aguilella Arzo G, Esparza Arroyo Á, Lillios KT, Mack J, Velasco-Vázquez J, Waterman A, Benítez de Lugo Enrich L, Benito Sánchez M, Agustí B, Codina F, de Prado G, Estalrrich A, Fernández Flores Á, Finlayson C, Finlayson G, Finlayson S, Giles-Guzmán F, Rosas A, Barciela González V, García Atiénzar G, Hernández Pérez MS, Llanos A, Carrión Marco Y, Collado Beneyto I, López-Serrano D, Sanz Tormo M, Valera AC, Bla… See abstract for full author list ➔ Olalde I, et al. Among authors: flores fernandez r. Science. 2019 Mar 15;363(6432):1230-1234. doi: 10.1126/science.aav4040. Science. 2019. PMID: 30872528 Free PMC article.
An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers.
Marciniak S, Bergey CM, Silva AM, Hałuszko A, Furmanek M, Veselka B, Velemínský P, Vercellotti G, Wahl J, Zariņa G, Longhi C, Kolář J, Garrido-Pena R, Flores-Fernández R, Herrero-Corral AM, Simalcsik A, Müller W, Sheridan A, Miliauskienė Ž, Jankauskas R, Moiseyev V, Köhler K, Király Á, Gamarra B, Cheronet O, Szeverényi V, Kiss V, Szeniczey T, Kiss K, Zoffmann ZK, Koós J, Hellebrandt M, Maier RM, Domboróczki L, Virag C, Novak M, Reich D, Hajdu T, von Cramon-Taubadel N, Pinhasi R, Perry GH. Marciniak S, et al. Among authors: flores fernandez r. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2106743119. doi: 10.1073/pnas.2106743119. Epub 2022 Apr 6. Proc Natl Acad Sci U S A. 2022. PMID: 35389750 Free PMC article.
Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum.
Flores-Fernández JM, Padilla-Camberos E, Fernández-Flores O, Diaz-Martínez NE, Barragán-Álvarez CP, Ramírez-Rodríguez PB. Flores-Fernández JM, et al. Exp Ther Med. 2019 Dec;18(6):4467-4472. doi: 10.3892/etm.2019.8093. Epub 2019 Oct 10. Exp Ther Med. 2019. PMID: 31777549 Free PMC article.
In the present study, an accurate and reliable approach using a murine model was pursued to evaluate the anti-ulcer activity, lipid peroxidation properties and acute toxicity of powdered dried stem of E. aschenbornianum. The results indicated that administration of E
In the present study, an accurate and reliable approach using a murine model was pursued to evaluate the anti-ulcer activity, lipid peroxida …
The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age.
Szécsényi-Nagy A, Roth C, Brandt G, Rihuete-Herrada C, Tejedor-Rodríguez C, Held P, García-Martínez-de-Lagrán Í, Arcusa Magallón H, Zesch S, Knipper C, Bánffy E, Friederich S, Meller H, Bueno Ramírez P, Barroso Bermejo R, de Balbín Behrmann R, Herrero-Corral AM, Flores Fernández R, Alonso Fernández C, Jiménez Echevarria J, Rindlisbacher L, Oliart C, Fregeiro MI, Soriano I, Vicente O, Micó R, Lull V, Soler Díaz J, López Padilla JA, Roca de Togores Muñoz C, Hernández Pérez MS, Jover Maestre FJ, Lomba Maurandi J, Avilés Fernández A, Lillios KT, Silva AM, Magalhães Ramalho M, Oosterbeek LM, Cunha C, Waterman AJ, Roig Buxó J, Martínez A, Ponce Martínez J, Hunt Ortiz M, Mejías-García JC, Pecero Espín JC, Cruz-Auñón Briones R, Tomé T, Carmona Ballestero E, Cardoso JL, Araújo AC, Liesau von Lettow-Vorbeck C, Blasco Bosqued C, Ríos Mendoza P, Pujante A, Royo-Guillén JI, Esquembre Beviá MA, Dos Santos Goncalves VM, Parreira R, Morán Hernández E, Méndez Izquierdo E, Vega Y Miguel J, Menduiña García R, Martínez Calvo V, López Jiménez O, Krause J, Pichler SL, Garrido-Pena R, Kunst M, Risch R, Rojo-Guerra MA, Haak W, Alt KW. Szécsényi-Nagy A, et al. Among authors: flores fernandez r. Sci Rep. 2017 Nov 15;7(1):15644. doi: 10.1038/s41598-017-15480-9. Sci Rep. 2017. PMID: 29142317 Free PMC article.
DNA methylases for site-selective inhibition of type IIS restriction enzyme activity.
Flores-Fernández CN, Lin D, Robins K, O'Callaghan CA. Flores-Fernández CN, et al. Appl Microbiol Biotechnol. 2024 Jan 25;108(1):174. doi: 10.1007/s00253-024-13015-7. Appl Microbiol Biotechnol. 2024. PMID: 38270650 Free PMC article.
In this work, ten methylases from type I and II R-M systems were selected for cloning and expression in E. coli strains tolerant to methylation. Isopropyl beta-D-1-thiogalactopyranoside (IPTG) concentrations and post-induction temperatures were tested to optimize the solub …
In this work, ten methylases from type I and II R-M systems were selected for cloning and expression in E. coli strains tolerant to m …
Two-step nanoprecipitation for the production of protein-loaded PLGA nanospheres.
Morales-Cruz M, Flores-Fernández GM, Morales-Cruz M, Orellano EA, Rodriguez-Martinez JA, Ruiz M, Griebenow K. Morales-Cruz M, et al. Among authors: flores fernandez gm. Results Pharma Sci. 2012;2:79-85. doi: 10.1016/j.rinphs.2012.11.001. Results Pharma Sci. 2012. PMID: 23316451 Free PMC article.
Future systems will have to be optimized to ascertain efficient cellular uptake of the nanoparticles by, e.g., surface modification with receptor ligands....
Future systems will have to be optimized to ascertain efficient cellular uptake of the nanoparticles by, e.g., surface modification w …
15 results