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Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
Ahmed HMM, Nimmagadda SC, Al-Matary YS, Fiori M, May T, Frank D, Patnana PK, Récher C, Schliemann C, Mikesch JH, Koenig T, Rosenbauer F, Hartmann W, Tuckermann J, Dührsen U, Lanying W, Dugas M, Opalka B, Lenz G, Khandanpour C. Ahmed HMM, et al. Among authors: al matary ys. Br J Haematol. 2022 Feb;196(4):995-1006. doi: 10.1111/bjh.17940. Epub 2021 Nov 18. Br J Haematol. 2022. PMID: 34792186
Enforced GFI1 expression impedes human and murine leukemic cell growth.
Hönes JM, Thivakaran A, Botezatu L, Patnana P, Castro SVDC, Al-Matary YS, Schütte J, Fischer KBI, Vassen L, Görgens A, Dührsen U, Giebel B, Khandanpour C. Hönes JM, et al. Among authors: al matary ys. Sci Rep. 2017 Nov 16;7(1):15720. doi: 10.1038/s41598-017-15866-9. Sci Rep. 2017. PMID: 29147018 Free PMC article.
Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome.
Thivakaran A, Botezatu L, Hönes JM, Schütte J, Vassen L, Al-Matary YS, Patnana P, Zeller A, Heuser M, Thol F, Gabdoulline R, Olberding N, Frank D, Suslo M, Köster R, Lennartz K, Görgens A, Giebel B, Opalka B, Dührsen U, Khandanpour C. Thivakaran A, et al. Among authors: al matary ys. Haematologica. 2018 Apr;103(4):614-625. doi: 10.3324/haematol.2017.167288. Epub 2018 Jan 11. Haematologica. 2018. PMID: 29326122 Free PMC article.
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.
Al-Matary YS, Botezatu L, Opalka B, Hönes JM, Lams RF, Thivakaran A, Schütte J, Köster R, Lennartz K, Schroeder T, Haas R, Dührsen U, Khandanpour C. Al-Matary YS, et al. Haematologica. 2016 Oct;101(10):1216-1227. doi: 10.3324/haematol.2016.143180. Epub 2016 Jul 7. Haematologica. 2016. PMID: 27390361 Free PMC article.