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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 2
1964 3
1965 1
1966 1
1967 2
1969 2
1970 1
1971 2
1972 5
1973 1
1974 3
1979 2
1980 1
1981 4
1982 2
1983 1
1984 1
1985 3
1986 5
1987 5
1988 11
1989 15
1990 17
1991 16
1992 14
1993 36
1994 35
1995 35
1996 48
1997 50
1998 74
1999 79
2000 84
2001 105
2002 118
2003 136
2004 177
2005 226
2006 253
2007 281
2008 299
2009 341
2010 391
2011 507
2012 550
2013 648
2014 713
2015 856
2016 887
2017 984
2018 1110
2019 1186
2020 1355
2021 1433
2022 1730
2023 1601
2024 848

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15,342 results

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Page 1
L-Theanine and Immunity: A Review.
Chen S, Kang J, Zhu H, Wang K, Han Z, Wang L, Liu J, Wu Y, He P, Tu Y, Li B. Chen S, et al. Among authors: han z. Molecules. 2023 May 1;28(9):3846. doi: 10.3390/molecules28093846. Molecules. 2023. PMID: 37175254 Free PMC article. Review.
L-theanine (N-ethyl-gamma-glutamine) is the main amino acid in tea leaves. ...Compared with its sedative and calming activities, the immunomodulatory effects of L-theanine have received less attention. Clinical and epidemiological studies have shown that L-th
L-theanine (N-ethyl-gamma-glutamine) is the main amino acid in tea leaves. ...Compared with its sedative and calming activities, the
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.
Kim S, Jo K, Hong KB, Han SH, Suh HJ. Kim S, et al. Among authors: han sh. Pharm Biol. 2019 Dec;57(1):65-73. doi: 10.1080/13880209.2018.1557698. Pharm Biol. 2019. PMID: 30707852 Free PMC article.
The use of GABA/l-theanine mixture rather than GABA or l-theanine alone restored to normal levels sleep time and quality in the arousal animal model. ...CONCLUSIONS: GABA/l-theanine mixture has a positive synergistic effect on sleep quality and duration as co …
The use of GABA/l-theanine mixture rather than GABA or l-theanine alone restored to normal levels sleep time and quality in th …
DsbA-L interacting with catalase in peroxisome improves tubular oxidative damage in diabetic nephropathy.
Liu Y, Chen W, Li C, Li L, Yang M, Jiang N, Luo S, Xi Y, Liu C, Han Y, Zhao H, Zhu X, Yuan S, Xiao L, Sun L. Liu Y, et al. Among authors: han y. Redox Biol. 2023 Oct;66:102855. doi: 10.1016/j.redox.2023.102855. Epub 2023 Aug 15. Redox Biol. 2023. PMID: 37597421 Free PMC article.
Additionally, the expression of DsbA-L in renal tubules of patients with DN significantly decreased and was positively correlated with peroxisomal function. Taken together, these results highlight an important role of DsbA-L in ameliorating tubular injury in DN by i …
Additionally, the expression of DsbA-L in renal tubules of patients with DN significantly decreased and was positively correlated wit …
L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes.
Hu S, Han M, Rezaei A, Li D, Wu G, Ma X. Hu S, et al. Among authors: han m. Curr Protein Pept Sci. 2017;18(6):599-608. doi: 10.2174/1389203717666160627074017. Curr Protein Pept Sci. 2017. PMID: 27356939 Review.
The potential molecular mechanism may play a role in modulating glucose homeostasis, promoting lipolysis, maintaining hormone levels, ameliorating insulin resistance, and fetal programing in early stages. The possible signaling pathway of the beneficial effects of L-argini …
The potential molecular mechanism may play a role in modulating glucose homeostasis, promoting lipolysis, maintaining hormone levels, amelio …
L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.
Kang L, Pang J, Zhang X, Liu Y, Wu Y, Wang J, Han D. Kang L, et al. Among authors: han d. J Nutr. 2023 Nov;153(11):3327-3340. doi: 10.1016/j.tjnut.2023.09.012. Epub 2023 Sep 15. J Nutr. 2023. PMID: 37717628
BACKGROUND: L-arabinose has anti-inflammatory and metabolism-promoting properties, and macrophages participate in the alleviation of inflammation; however, the mechanism by which they contribute to the anti-inflammatory effects of L-arabinose is unknown. ...METHODS: …
BACKGROUND: L-arabinose has anti-inflammatory and metabolism-promoting properties, and macrophages participate in the alleviation of …
Aromatic L-amino acid decarboxylases: mechanistic features and microbial applications.
Han SW, Shin JS. Han SW, et al. Appl Microbiol Biotechnol. 2022 Jun;106(12):4445-4458. doi: 10.1007/s00253-022-12028-4. Epub 2022 Jun 28. Appl Microbiol Biotechnol. 2022. PMID: 35763068 Review.
Aromatic L-amino acid decarboxylases (AADCs) catalyze the conversion of aromatic L-amino acids into aromatic monoamines that play diverse physiological and biosynthetic roles in living organisms. ...Microbial applications of aromatic L-amino acid decarboxylas …
Aromatic L-amino acid decarboxylases (AADCs) catalyze the conversion of aromatic L-amino acids into aromatic monoamines that p …
DsbA-L alleviates tubular injury in diabetic nephropathy by activating mitophagy through maintenance of MAM integrity.
Yang M, Zhang Q, Luo S, Han Y, Zhao H, Jiang N, Liu Y, Li L, Li C, Liu C, He L, Zhu X, Liu Y, Sun L. Yang M, et al. Among authors: han y. Clin Sci (Lond). 2023 Jun 28;137(12):931-945. doi: 10.1042/CS20220787. Clin Sci (Lond). 2023. PMID: 37226722
Furthermore, notably decreased expression of ATG14 and Beclin1 in MAMs extracted from the kidneys of diabetic DsbA-L-/- mice was observed. In vitro, overexpression of DsbA-L reversed the disruption of MAM integrity and enhanced mitophagy in HK-2 cells, a human proxi …
Furthermore, notably decreased expression of ATG14 and Beclin1 in MAMs extracted from the kidneys of diabetic DsbA-L-/- mice was obse …
Genetic modification and bioprocess optimization for S-Adenosyl-L-methionine biosynthesis.
Hu X, Quinn PJ, Wang Z, Han G, Wang X. Hu X, et al. Among authors: han g. Subcell Biochem. 2012;64:327-41. doi: 10.1007/978-94-007-5055-5_16. Subcell Biochem. 2012. PMID: 23080258 Review.
S-Adenosyl-L-methionine is an important bioactive sulfur-containing amino acid. Large scale preparation of the amino acid is of great significance. S-Adenosyl-L-methionine can be synthesized from L-methionine and adenosine triphosphate in a reaction catalyzed …
S-Adenosyl-L-methionine is an important bioactive sulfur-containing amino acid. Large scale preparation of the amino acid is of great …
Origin of the OAS-RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering.
Chu L, Gong Z, Wang W, Han GZ. Chu L, et al. Among authors: han gz. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2304687120. doi: 10.1073/pnas.2304687120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487089 Free PMC article.
Sensing double-stranded RNA as nonself, the 2',5'-oligoadenylate synthetase (OAS)-ribonuclease L (RNase L) pathway represents a crucial component of innate immunity. ...Multiple concerted losses of OAS and RNase L occurred during the evolution of jawed verteb …
Sensing double-stranded RNA as nonself, the 2',5'-oligoadenylate synthetase (OAS)-ribonuclease L (RNase L) pathway represents …
Applications of leukocyte- and platelet-rich plasma (L-PRP) in trauma surgery.
Yuan T, Guo SC, Han P, Zhang CQ, Zeng BF. Yuan T, et al. Among authors: han p. Curr Pharm Biotechnol. 2012 Jun;13(7):1173-84. doi: 10.2174/138920112800624445. Curr Pharm Biotechnol. 2012. PMID: 21740374 Review.
L-PRP is now playing an increasing role in the management of patients with traumatic injuries. However, most studies are only anecdotal or case reports, and then larger controlled studies are needed. This article introduces the reader to L-PRP properties and L
L-PRP is now playing an increasing role in the management of patients with traumatic injuries. However, most studies are only anecdot
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