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Selective CDK9 Inhibition by Natural Compound Toyocamycin in Cancer Cells.
Pandey S, Djibo R, Darracq A, Calendo G, Zhang H, Henry RA, Andrews AJ, Baylin SB, Madzo J, Najmanovich R, Issa JJ, Raynal NJ. Pandey S, et al. Among authors: darracq a. Cancers (Basel). 2022 Jul 8;14(14):3340. doi: 10.3390/cancers14143340. Cancers (Basel). 2022. PMID: 35884401 Free PMC article.
Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.
Uriarte M, Sen Nkwe N, Tremblay R, Ahmed O, Messmer C, Mashtalir N, Barbour H, Masclef L, Voide M, Viallard C, Daou S, Abdelhadi D, Ronato D, Paydar M, Darracq A, Boulay K, Desjardins-Lecavalier N, Sapieha P, Masson JY, Sergeev M, Kwok BH, Hulea L, Mallette FA, Milot E, Larrivée B, Wurtele H, Affar EB. Uriarte M, et al. Among authors: darracq a. Nat Commun. 2021 Nov 30;12(1):6984. doi: 10.1038/s41467-021-27306-4. Nat Commun. 2021. PMID: 34848715 Free PMC article.
MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells.
Bottardi S, Guieze R, Bourgoin V, Fotouhi-Ardakani N, Dougé A, Darracq A, Lakehal YA, Berger MG, Mollica L, Bay JO, Omichinski JG, Milot E. Bottardi S, et al. Among authors: darracq a. Exp Hematol. 2020 Aug;88:68-82.e5. doi: 10.1016/j.exphem.2020.07.004. Epub 2020 Jul 16. Exp Hematol. 2020. PMID: 32682001 Free article.
Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion.
Beaudry A, Jacques-Ricard S, Darracq A, Sgarioto N, Garcia A, García TR, Lemieux W, Béland K, Haddad E, Cordeiro P, Duval M, McGraw S, Richer C, Caron M, Marois F, St-Onge P, Sinnett D, Banquy X, Raynal NJ. Beaudry A, et al. Among authors: darracq a. Sci Rep. 2023 Sep 30;13(1):16443. doi: 10.1038/s41598-023-43219-2. Sci Rep. 2023. PMID: 37777587 Free PMC article.