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Page 1
Different responses to DNA damage determine ageing differences between organs.
Vougioukalaki M, Demmers J, Vermeij WP, Baar M, Bruens S, Magaraki A, Kuijk E, Jager M, Merzouk S, Brandt RMC, Kouwenberg J, van Boxtel R, Cuppen E, Pothof J, Hoeijmakers JHJ. Vougioukalaki M, et al. Among authors: merzouk s. Aging Cell. 2022 Apr;21(4):e13562. doi: 10.1111/acel.13562. Epub 2022 Mar 4. Aging Cell. 2022. PMID: 35246937 Free PMC article.
SPEN is required for Xist upregulation during initiation of X chromosome inactivation.
Robert-Finestra T, Tan BF, Mira-Bontenbal H, Timmers E, Gontan C, Merzouk S, Giaimo BD, Dossin F, van IJcken WFJ, Martens JWM, Borggrefe T, Heard E, Gribnau J. Robert-Finestra T, et al. Among authors: merzouk s. Nat Commun. 2021 Dec 1;12(1):7000. doi: 10.1038/s41467-021-27294-5. Nat Commun. 2021. PMID: 34853312 Free PMC article.
CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells.
Soochit W, Sleutels F, Stik G, Bartkuhn M, Basu S, Hernandez SC, Merzouk S, Vidal E, Boers R, Boers J, van der Reijden M, Geverts B, van Cappellen WA, van den Hout M, Ozgur Z, van IJcken WFJ, Gribnau J, Renkawitz R, Graf T, Houtsmuller A, Grosveld F, Stadhouders R, Galjart N. Soochit W, et al. Among authors: merzouk s. Nat Cell Biol. 2021 Aug;23(8):881-893. doi: 10.1038/s41556-021-00722-w. Epub 2021 Jul 29. Nat Cell Biol. 2021. PMID: 34326481