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Antigen-presenting innate lymphoid cells orchestrate neuroinflammation.
Grigg JB, Shanmugavadivu A, Regen T, Parkhurst CN, Ahmed A, Joseph AM, Mazzucco M, Gronke K, Diefenbach A, Eberl G, Vartanian T, Waisman A, Sonnenberg GF. Grigg JB, et al. Among authors: shanmugavadivu a. Nature. 2021 Dec;600(7890):707-712. doi: 10.1038/s41586-021-04136-4. Epub 2021 Dec 1. Nature. 2021. PMID: 34853467 Free PMC article.
IL-17 controls central nervous system autoimmunity through the intestinal microbiome.
Regen T, Isaac S, Amorim A, Núñez NG, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. Regen T, et al. Among authors: shanmugavadivu a. Sci Immunol. 2021 Feb 5;6(56):eaaz6563. doi: 10.1126/sciimmunol.aaz6563. Sci Immunol. 2021. PMID: 33547052
Expression of IL-17F is associated with non-pathogenic Th17 cells.
Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC, Waisman A. Wanke F, et al. Among authors: shanmugavadivu a. J Mol Med (Berl). 2018 Aug;96(8):819-829. doi: 10.1007/s00109-018-1662-5. Epub 2018 Jun 29. J Mol Med (Berl). 2018. PMID: 29959474