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Page 1
The non-coding RNA landscape of human hematopoiesis and leukemia.
Schwarzer A, Emmrich S, Schmidt F, Beck D, Ng M, Reimer C, Adams FF, Grasedieck S, Witte D, Käbler S, Wong JWH, Shah A, Huang Y, Jammal R, Maroz A, Jongen-Lavrencic M, Schambach A, Kuchenbauer F, Pimanda JE, Reinhardt D, Heckl D, Klusmann JH. Schwarzer A, et al. Among authors: grasedieck s. Nat Commun. 2017 Aug 9;8(1):218. doi: 10.1038/s41467-017-00212-4. Nat Commun. 2017. PMID: 28794406 Free PMC article.
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck S, Cabantog A, MacPhee L, Im J, Ruess C, Demir B, Sperb N, Rücker FG, Döhner K, Herold T, Pollack JR, Bullinger L, Rouhi A, Kuchenbauer F. Grasedieck S, et al. Haematologica. 2022 Aug 1;107(8):1758-1772. doi: 10.3324/haematol.2021.276048. Haematologica. 2022. PMID: 34854277 Free PMC article.
Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia.
Niu X, Rothe K, Chen M, Grasedieck S, Li R, Nam SE, Zhang X, Novakovskiy GE, Ahn YH, Maksakova I, Lai S, Zhang H, Yan J, Liu H, Zhao Y, Wu D, Ge Y, Wasserman WW, Rouhi A, Kuchenbauer F, Yip CK, Zhang Z, Jiang X. Niu X, et al. Among authors: grasedieck s. Blood. 2021 Jul 1;137(26):3641-3655. doi: 10.1182/blood.2020007651. Blood. 2021. PMID: 33786587 Free PMC article.
MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
Schneider E, Pochert N, Ruess C, MacPhee L, Escano L, Miller C, Krowiorz K, Delsing Malmberg E, Heravi-Moussavi A, Lorzadeh A, Ashouri A, Grasedieck S, Sperb N, Kumar Kopparapu P, Iben S, Staffas A, Xiang P, Rösler R, Kanduri M, Larsson E, Fogelstrand L, Döhner H, Döhner K, Wiese S, Hirst M, Keith Humphries R, Palmqvist L, Kuchenbauer F, Rouhi A. Schneider E, et al. Among authors: grasedieck s. Leukemia. 2020 May;34(5):1253-1265. doi: 10.1038/s41375-019-0651-1. Epub 2019 Nov 25. Leukemia. 2020. PMID: 31768018
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Hirsch S, Blätte TJ, Grasedieck S, Cocciardi S, Rouhi A, Jongen-Lavrencic M, Paschka P, Krönke J, Gaidzik VI, Döhner H, Schlenk RF, Kuchenbauer F, Döhner K, Dolnik A, Bullinger L. Hirsch S, et al. Among authors: grasedieck s. Haematologica. 2017 Dec;102(12):2039-2047. doi: 10.3324/haematol.2017.172866. Epub 2017 Sep 29. Haematologica. 2017. PMID: 28971903 Free PMC article.
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