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Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.
Moles E, Howard CB, Huda P, Karsa M, McCalmont H, Kimpton K, Duly A, Chen Y, Huang Y, Tursky ML, Ma D, Bustamante S, Pickford R, Connerty P, Omari S, Jolly CJ, Joshi S, Shen S, Pimanda JE, Dolnikov A, Cheung LC, Kotecha RS, Norris MD, Haber M, de Bock CE, Somers K, Lock RB, Thurecht KJ, Kavallaris M. Moles E, et al. Among authors: omari s. Sci Transl Med. 2023 May 17;15(696):eabm1262. doi: 10.1126/scitranslmed.abm1262. Epub 2023 May 17. Sci Transl Med. 2023. PMID: 37196067
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Van Thillo Q, De Bie J, Seneviratne JA, Demeyer S, Omari S, Balachandran A, Zhai V, Tam WL, Sweron B, Geerdens E, Gielen O, Provost S, Segers H, Boeckx N, Marshall GM, Cheung BB, Isobe K, Kato I, Takita J, Amos TG, Deveson IW, McCalmont H, Lock RB, Oxley EP, Garwood MM, Dickins RA, Uyttebroeck A, Carter DR, Cools J, de Bock CE. Van Thillo Q, et al. Among authors: omari s. Nat Commun. 2021 Jul 6;12(1):4164. doi: 10.1038/s41467-021-24442-9. Nat Commun. 2021. PMID: 34230493 Free PMC article.
A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice.
Boast B, Miosge LA, Kuehn HS, Cho V, Athanasopoulos V, McNamara HA, Sontani Y, Mei Y, Howard D, Sutton HJ, Omari SA, Yu Z, Nasreen M, Andrews TD, Cockburn IA, Goodnow CC, Rosenzweig SD, Enders A. Boast B, et al. Among authors: omari sa. J Immunol. 2021 Apr 1;206(7):1505-1514. doi: 10.4049/jimmunol.1901464. Epub 2021 Mar 3. J Immunol. 2021. PMID: 33658297 Free PMC article.