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Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.
Akimova T, Zhang T, Christensen LM, Wang Z, Han R, Negorev D, Samanta A, Sasson IE, Gaddapara T, Jiao J, Wang L, Bhatti TR, Levine MH, Diamond JM, Beier UH, Simmons RA, Cantu E, Wilkes DS, Lederer DJ, Anderson M, Christie JD, Hancock WW. Akimova T, et al. Among authors: christensen lm. Am J Respir Crit Care Med. 2021 Nov 1;204(9):1060-1074. doi: 10.1164/rccm.202012-4306OC. Am J Respir Crit Care Med. 2021. PMID: 34346860 Free PMC article.
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
Siska PJ, Jiao J, Matos C, Singer K, Berger RS, Dettmer K, Oefner PJ, Cully MD, Wang Z, QuinnIII WJ, Oliff KN, Wilkins BJ, Christensen LM, Wang L, Hancock WW, Baur JA, Levine MH, Ugele I, Mayr R, Renner K, Zhou L, Kreutz M, Beier UH. Siska PJ, et al. Among authors: christensen lm. EBioMedicine. 2021 Dec;74:103734. doi: 10.1016/j.ebiom.2021.103734. Epub 2021 Dec 4. EBioMedicine. 2021. PMID: 34875457 Free PMC article.