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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 4
2006 4
2007 2
2008 5
2009 3
2010 4
2011 3
2012 4
2013 4
2014 4
2015 3
2016 3
2018 4
2019 3
2020 11
2021 2
2022 1
2024 0

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59 results

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Page 1
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.
Weaver RJ, Blomme EA, Chadwick AE, Copple IM, Gerets HHJ, Goldring CE, Guillouzo A, Hewitt PG, Ingelman-Sundberg M, Jensen KG, Juhila S, Klingmüller U, Labbe G, Liguori MJ, Lovatt CA, Morgan P, Naisbitt DJ, Pieters RHH, Snoeys J, van de Water B, Williams DP, Park BK. Weaver RJ, et al. Among authors: williams dp. Nat Rev Drug Discov. 2020 Feb;19(2):131-148. doi: 10.1038/s41573-019-0048-x. Epub 2019 Nov 20. Nat Rev Drug Discov. 2020. PMID: 31748707 Free article. Review.
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
Thompson RA, Isin EM, Ogese MO, Mettetal JT, Williams DP. Thompson RA, et al. Among authors: williams dp. Chem Res Toxicol. 2016 Apr 18;29(4):505-33. doi: 10.1021/acs.chemrestox.5b00410. Epub 2016 Jan 6. Chem Res Toxicol. 2016. PMID: 26735163 Review.
Managing the challenge of chemically reactive metabolites in drug development.
Park BK, Boobis A, Clarke S, Goldring CE, Jones D, Kenna JG, Lambert C, Laverty HG, Naisbitt DJ, Nelson S, Nicoll-Griffith DA, Obach RS, Routledge P, Smith DA, Tweedie DJ, Vermeulen N, Williams DP, Wilson ID, Baillie TA. Park BK, et al. Among authors: williams dp. Nat Rev Drug Discov. 2011 Apr;10(4):292-306. doi: 10.1038/nrd3408. Nat Rev Drug Discov. 2011. PMID: 21455238 Review.
Investigation of toxic metabolites during drug development.
Park K, Williams DP, Naisbitt DJ, Kitteringham NR, Pirmohamed M. Park K, et al. Among authors: williams dp. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):425-34. doi: 10.1016/j.taap.2005.02.029. Toxicol Appl Pharmacol. 2005. PMID: 15996699 Review.
Acyl glucuronides: the good, the bad and the ugly.
Regan SL, Maggs JL, Hammond TG, Lambert C, Williams DP, Park BK. Regan SL, et al. Among authors: williams dp. Biopharm Drug Dispos. 2010 Oct;31(7):367-95. doi: 10.1002/bdd.720. Biopharm Drug Dispos. 2010. PMID: 20830700 Review.
Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies.
Heslop JA, Hammond TG, Santeramo I, Tort Piella A, Hopp I, Zhou J, Baty R, Graziano EI, Proto Marco B, Caron A, Sköld P, Andrews PW, Baxter MA, Hay DC, Hamdam J, Sharpe ME, Patel S, Jones DR, Reinhardt J, Danen EH, Ben-David U, Stacey G, Björquist P, Piner J, Mills J, Rowe C, Pellegrini G, Sethu S, Antoine DJ, Cross MJ, Murray P, Williams DP, Kitteringham NR, Goldring CE, Park BK. Heslop JA, et al. Among authors: williams dp. Stem Cells Transl Med. 2015 Apr;4(4):389-400. doi: 10.5966/sctm.2014-0110. Epub 2015 Feb 26. Stem Cells Transl Med. 2015. PMID: 25722427 Free PMC article. Review.
The role of metabolic activation in drug-induced hepatotoxicity.
Park BK, Kitteringham NR, Maggs JL, Pirmohamed M, Williams DP. Park BK, et al. Among authors: williams dp. Annu Rev Pharmacol Toxicol. 2005;45:177-202. doi: 10.1146/annurev.pharmtox.45.120403.100058. Annu Rev Pharmacol Toxicol. 2005. PMID: 15822174 Review.
The generation, detection, and effects of reactive drug metabolites.
Stachulski AV, Baillie TA, Park BK, Obach RS, Dalvie DK, Williams DP, Srivastava A, Regan SL, Antoine DJ, Goldring CE, Chia AJ, Kitteringham NR, Randle LE, Callan H, Castrejon JL, Farrell J, Naisbitt DJ, Lennard MS. Stachulski AV, et al. Among authors: williams dp. Med Res Rev. 2013 Sep;33(5):985-1080. doi: 10.1002/med.21273. Epub 2012 Oct 22. Med Res Rev. 2013. PMID: 23090860 Review.
59 results