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Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.
Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB, Jüppner H, Wein MN, Rhee EP. Simic P, et al. Among authors: aziz nb. J Clin Invest. 2020 Mar 2;130(3):1513-1526. doi: 10.1172/JCI131190. J Clin Invest. 2020. PMID: 32065590 Free PMC article.
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.
Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. Do BT, et al. Among authors: aziz n. Dev Cell. 2024 May 30:S1534-5807(24)00327-7. doi: 10.1016/j.devcel.2024.05.010. Online ahead of print. Dev Cell. 2024. PMID: 38823395