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Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression.
Mol Cell. 2021 May 6;81(9):2041-2052.e6. doi: 10.1016/j.molcel.2021.03.018. Epub 2021 Apr 5.
Mol Cell. 2021.
PMID: 33823141
Free article.
Pharmacological CDK4/6 inhibition reveals a p53-dependent senescent state with restricted toxicity.
Wang B, Varela-Eirin M, Brandenburg SM, Hernandez-Segura A, van Vliet T, Jongbloed EM, Wilting SM, Ohtani N, Jager A, Demaria M.
Wang B, et al. Among authors: van vliet t.
EMBO J. 2022 Mar 15;41(6):e108946. doi: 10.15252/embj.2021108946. Epub 2022 Jan 5.
EMBO J. 2022.
PMID: 34985783
Free PMC article.
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Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche.
Peng X, Wu Y, Brouwer U, van Vliet T, Wang B, Demaria M, Barazzuol L, Coppes RP.
Peng X, et al. Among authors: van vliet t.
Cell Death Dis. 2020 Oct 14;11(10):854. doi: 10.1038/s41419-020-03074-9.
Cell Death Dis. 2020.
PMID: 33056980
Free PMC article.
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The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon.
Fontana L, Mitchell SE, Wang B, Tosti V, van Vliet T, Veronese N, Bertozzi B, Early DS, Maissan P, Speakman JR, Demaria M.
Fontana L, et al. Among authors: van vliet t.
Aging Cell. 2018 Jun;17(3):e12746. doi: 10.1111/acel.12746. Epub 2018 Mar 25.
Aging Cell. 2018.
PMID: 29575469
Free PMC article.
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