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Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing.
Biol Open. 2022 Jan 15;11(1):bio058978. doi: 10.1242/bio.058978. Epub 2022 Jan 12.
Biol Open. 2022.
PMID: 35019138
Free PMC article.
MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells.
Franck S, Barbé L, Ardui S, De Vlaeminck Y, Allemeersch J, Dziedzicka D, Spits C, Vanroye F, Hilven P, Duqué G, Vermeesch JR, Gheldof A, Sermon K.
Franck S, et al. Among authors: duque g.
Hum Mol Genet. 2021 Jan 6;29(21):3566-3577. doi: 10.1093/hmg/ddaa250.
Hum Mol Genet. 2021.
PMID: 33242073
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