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Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Ramdas B, Yuen LD, Palam LR, Patel R, Pasupuleti SK, Jideonwo V, Zhang J, Maguire C, Wong E, Kanumuri R, Zhang C, Sandusky G, Chan RJ, Zhang C, Stieglitz E, Haneline L, Kapur R. Ramdas B, et al. Among authors: maguire c. Mol Ther. 2022 Jul 6;30(7):2505-2521. doi: 10.1016/j.ymthe.2022.04.009. Epub 2022 Apr 20. Mol Ther. 2022. PMID: 35443935 Free PMC article.
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Kumar B, Adebayo AK, Prasad M, Capitano ML, Wang R, Bhat-Nakshatri P, Anjanappa M, Simpson E, Chen D, Liu Y, Schilder JM, Colter AB, Maguire C, Temm CJ, Sandusky G, Doud EH, Wijeratne AB, Mosley AL, Broxmeyer HE, Nakshatri H. Kumar B, et al. Among authors: maguire c. Sci Adv. 2022 Jan 14;8(2):eabh3375. doi: 10.1126/sciadv.abh3375. Epub 2022 Jan 12. Sci Adv. 2022. PMID: 35020422 Free PMC article.
Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions.
Chen F, Licarete E, Wu X, Petrusca D, Maguire C, Jacobsen M, Colter A, Sandusky GE, Czader M, Capitano ML, Ropa JP, Boswell HS, Carta F, Supuran CT, Parkin B, Fishel ML, Konig H. Chen F, et al. Among authors: maguire c. J Cell Mol Med. 2021 Dec;25(24):11039-11052. doi: 10.1111/jcmm.17027. Epub 2021 Nov 17. J Cell Mol Med. 2021. PMID: 34791807 Free PMC article.