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Genome-wide screens identify specific drivers of mutant hTERT promoters.
Shanmugam R, Ozturk MB, Low JL, Akincilar SC, Chua JYH, Thangavelu MT, Periyasamy G, DasGupta R, Tergaonkar V. Shanmugam R, et al. Among authors: thangavelu mt. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2105171119. doi: 10.1073/pnas.2105171119. Proc Natl Acad Sci U S A. 2022. PMID: 35027447 Free PMC article.
Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.
Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R. Sharma A, et al. Among authors: thangavelu mt. Nat Commun. 2018 Nov 22;9(1):4931. doi: 10.1038/s41467-018-07261-3. Nat Commun. 2018. PMID: 30467425 Free PMC article.
Corrigendum to 'A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)'.
Low JL, Lau DP, Zhang X, Kwang XL, Rohatgi N, Chan JV, Chong FT, Wong SQR, Leong HS, Thangavelu MT, Rikka S, Skanderup AMJ, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. Low JL, et al. Among authors: thangavelu mt. EBioMedicine. 2021 Apr;66:103297. doi: 10.1016/j.ebiom.2021.103297. Epub 2021 Apr 14. EBioMedicine. 2021. PMID: 33862587 Free PMC article. No abstract available.
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).
Low JL, Lau DP, Zhang X, Kwang XL, Rohatgi N, Chan JV, Chong FT, Wong SQR, Leong HS, Thangavelu MT, Rikka S, Skanderup AMJ, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. Low JL, et al. Among authors: thangavelu mt. EBioMedicine. 2021 Feb;64:103220. doi: 10.1016/j.ebiom.2021.103220. Epub 2021 Jan 30. EBioMedicine. 2021. PMID: 33529999 Free PMC article.