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Page 1
Design and Optimization of Novel Benzimidazole- and Imidazo[4,5-b]pyridine-Based ATM Kinase Inhibitors with Subnanomolar Activities.
Dimitrov T, Moschopoulou AA, Seidel L, Kronenberger T, Kudolo M, Poso A, Geibel C, Wölffing P, Dauch D, Zender L, Schollmeyer D, Bajorath J, Forster M, Laufer S. Dimitrov T, et al. Among authors: geibel c. J Med Chem. 2023 Jun 8;66(11):7304-7330. doi: 10.1021/acs.jmedchem.2c02104. Epub 2023 May 25. J Med Chem. 2023. PMID: 37226670
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Andreev S, Pantsar T, Tesch R, Kahlke N, El-Gokha A, Ansideri F, Grätz L, Romasco J, Sita G, Geibel C, Lämmerhofer M, Tarozzi A, Knapp S, Laufer SA, Koch P. Andreev S, et al. Among authors: geibel c. J Med Chem. 2022 Jan 27;65(2):1283-1301. doi: 10.1021/acs.jmedchem.0c02146. Epub 2021 Jul 2. J Med Chem. 2022. PMID: 34213342
High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin.
Aryal N, Chen J, Bhattarai K, Hennrich O, Handayani I, Kramer M, Straetener J, Wommer T, Berscheid A, Peter S, Reiling N, Brötz-Oesterhelt H, Geibel C, Lämmerhofer M, Mast Y, Gross H. Aryal N, et al. Among authors: geibel c. J Nat Prod. 2022 Mar 25;85(3):530-539. doi: 10.1021/acs.jnatprod.1c01051. Epub 2022 Mar 9. J Nat Prod. 2022. PMID: 35263115
17 results