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Redox regulation of cell state and fate.
Lee BWL, Ghode P, Ong DST. Lee BWL, et al. Redox Biol. 2019 Jul;25:101056. doi: 10.1016/j.redox.2018.11.014. Epub 2018 Nov 23. Redox Biol. 2019. PMID: 30509603 Free PMC article. Review.
CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.
Chuah YH, Tay EXY, Grinchuk OV, Yoon J, Feng J, Kannan S, Robert M, Jakhar R, Liang Y, Lee BWL, Wang LC, Lim YT, Zhao T, Sobota RM, Lu G, Low BC, Crasta KC, Verma CS, Lin Z, Ong DST. Chuah YH, et al. Among authors: lee bwl. Cell Death Differ. 2023 Aug;30(8):1973-1987. doi: 10.1038/s41418-023-01192-3. Epub 2023 Jul 19. Cell Death Differ. 2023. PMID: 37468549 Free PMC article.
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity.
Yoon J, Grinchuk OV, Tirado-Magallanes R, Ngian ZK, Tay EXY, Chuah YH, Lee BWL, Feng J, Crasta KC, Ong CT, Benoukraf T, Ong DST. Yoon J, et al. Among authors: lee bwl. Cell Death Differ. 2022 Jul;29(7):1379-1394. doi: 10.1038/s41418-021-00926-5. Epub 2022 Jan 20. Cell Death Differ. 2022. PMID: 35058574 Free PMC article.
A chemical biology approach reveals a dependency of glioblastoma on biotin distribution.
Yoon J, Grinchuk OV, Kannan S, Ang MJY, Li Z, Tay EXY, Lok KZ, Lee BWL, Chuah YH, Chia K, Tirado Magallanes R, Liu C, Zhao H, Hor JH, Lim JJ, Benoukraf T, Toh TB, Chow EK, Kovalik JP, Ching J, Ng SY, Koh MJ, Liu X, Verma CS, Ong DST. Yoon J, et al. Among authors: lee bwl. Sci Adv. 2021 Sep 3;7(36):eabf6033. doi: 10.1126/sciadv.abf6033. Epub 2021 Sep 3. Sci Adv. 2021. PMID: 34516894 Free PMC article.