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Year Number of Results
2018 3
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2020 4
2021 1
2022 3
2023 2
2024 1

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Page 1
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D, Balka KR, Calleja DJ, Moghaddas F, Ni E, McLean CA, Samson AL, Tyebji S, Tonkin CJ, Bye CR, Turner BJ, Pepin G, Gantier MP, Rogers KL, McArthur K, Crouch PJ, Masters SL. Yu CH, et al. Among authors: balka kr. Cell. 2020 Oct 29;183(3):636-649.e18. doi: 10.1016/j.cell.2020.09.020. Epub 2020 Oct 7. Cell. 2020. PMID: 33031745 Free PMC article.
Termination of STING responses is mediated via ESCRT-dependent degradation.
Balka KR, Venkatraman R, Saunders TL, Shoppee A, Pang ES, Magill Z, Homman-Ludiye J, Huang C, Lane RM, York HM, Tan P, Schittenhelm RB, Arumugam S, Kile BT, O'Keeffe M, De Nardo D. Balka KR, et al. EMBO J. 2023 Jun 15;42(12):e112712. doi: 10.15252/embj.2022112712. Epub 2023 May 4. EMBO J. 2023. PMID: 37139896 Free PMC article.
Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: balka kr. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
Genistein Targets STING-Driven Antiviral Responses.
Ullah TR, Balka KR, Ambrose RL, Pépin G, Wilce MCJ, Wilce JA, Thomas BJ, De Nardo D, Williams BRG, Gantier MP. Ullah TR, et al. Among authors: balka kr. mBio. 2022 Aug 30;13(4):e0206422. doi: 10.1128/mbio.02064-22. Epub 2022 Aug 4. mBio. 2022. PMID: 35924852 Free PMC article.
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy.
Saunders TL, Windley SP, Gervinskas G, Balka KR, Rowe C, Lane R, Tailler M, Nguyen TN, Ramm G, Lazarou M, De Nardo D, Kile BT, McArthur K. Saunders TL, et al. Among authors: balka kr. Cell Death Differ. 2024 Mar;31(3):335-347. doi: 10.1038/s41418-024-01260-2. Epub 2024 Feb 23. Cell Death Differ. 2024. PMID: 38396150 Free PMC article.
Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations.
Pang ES, Daraj G, Balka KR, De Nardo D, Macri C, Hochrein H, Masterman KA, Tan PS, Shoppee A, Magill Z, Jahan N, Bafit M, Zhan Y, Kile BT, Lawlor KE, Radford KJ, Wright MD, O'Keeffe M. Pang ES, et al. Among authors: balka kr. Front Immunol. 2022 Feb 25;13:794776. doi: 10.3389/fimmu.2022.794776. eCollection 2022. Front Immunol. 2022. PMID: 35281062 Free PMC article.
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24.
Davidson S, Yu CH, Steiner A, Ebstein F, Baker PJ, Jarur-Chamy V, Hrovat Schaale K, Laohamonthonkul P, Kong K, Calleja DJ, Harapas CR, Balka KR, Mitchell J, Jackson JT, Geoghegan ND, Moghaddas F, Rogers KL, Mayer-Barber KD, De Jesus AA, De Nardo D, Kile BT, Sadler AJ, Poli MC, Krüger E, Goldbach Mansky R, Masters SL. Davidson S, et al. Among authors: balka kr. Sci Immunol. 2022 Feb 11;7(68):eabi6763. doi: 10.1126/sciimmunol.abi6763. Epub 2022 Feb 11. Sci Immunol. 2022. PMID: 35148201 Free PMC article.
13 results