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Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.
Wang E, Mi X, Thompson MC, Montoya S, Notti RQ, Afaghani J, Durham BH, Penson A, Witkowski MT, Lu SX, Bourcier J, Hogg SJ, Erickson C, Cui D, Cho H, Singer M, Totiger TM, Chaudhry S, Geyer M, Alencar A, Linley AJ, Palomba ML, Coombs CC, Park JH, Zelenetz A, Roeker L, Rosendahl M, Tsai DE, Ebata K, Brandhuber B, Hyman DM, Aifantis I, Mato A, Taylor J, Abdel-Wahab O. Wang E, et al. Among authors: linley aj. N Engl J Med. 2022 Feb 24;386(8):735-743. doi: 10.1056/NEJMoa2114110. N Engl J Med. 2022. PMID: 35196427 Free PMC article.
Poor prognosis is ZAP70'ed into focus in CLL.
Linley AJ, Slupsky JR. Linley AJ, et al. Blood. 2021 Jul 1;137(26):3586-3587. doi: 10.1182/blood.2021011270. Blood. 2021. PMID: 34196683 Free article. No abstract available.
Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells.
Linley AJ, Karydis LI, Mondru AK, D'Avola A, Al Shmrany H, Cicconi S, Griffin R, Forconi F, Pettitt AR, Kalakonda N, Rawstron AC, Hillmen P, Steele AJ, MacEwan DJ, Packham G, Prior IA, Slupsky JR. Linley AJ, et al. Clin Cancer Res. 2021 Oct 15;27(20):5647-5659. doi: 10.1158/1078-0432.CCR-21-0161. Epub 2021 Aug 11. Clin Cancer Res. 2021. PMID: 34380642 Free PMC article.