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Aβ∗56 is a stable oligomer that impairs memory function in mice.
Liu P, Lapcinski IP, Hlynialuk CJW, Steuer EL, Loude TJ Jr, Shapiro SL, Kemper LJ, Ashe KH. Liu P, et al. Among authors: shapiro sl. iScience. 2024 Feb 15;27(3):109239. doi: 10.1016/j.isci.2024.109239. eCollection 2024 Mar 15. iScience. 2024. PMID: 38433923 Free PMC article.
Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.
Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L. Peng Y, et al. Among authors: shapiro sl. Aging Cell. 2018 Oct;17(5):e12820. doi: 10.1111/acel.12820. Epub 2018 Jul 27. Aging Cell. 2018. PMID: 30051577 Free PMC article.