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Page 1
Fas-associated factor 1 induces the accumulation of α-synuclein through autophagic suppression in dopaminergic neurons.
FASEB J. 2021 Apr;35(4):e21363. doi: 10.1096/fj.202001371RR.
FASEB J. 2021.
PMID: 33749937
Pharmacological Intervention Targeting FAF1 Restores Autophagic Flux for α-Synuclein Degradation in the Brain of a Parkinson's Disease Mouse Model.
Kim BS, Song JA, Jang KH, Jang T, Jung B, Yoo SE, Lee JM, Kim E.
Kim BS, et al.
ACS Chem Neurosci. 2022 Mar 16;13(6):806-817. doi: 10.1021/acschemneuro.1c00828. Epub 2022 Mar 1.
ACS Chem Neurosci. 2022.
PMID: 35230076
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A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission.
Park G, Kim BS, Kim E.
Park G, et al. Among authors: kim bs.
Cell Commun Signal. 2020 Aug 24;18(1):133. doi: 10.1186/s12964-020-00632-8.
Cell Commun Signal. 2020.
PMID: 32831099
Free PMC article.
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FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
Yu C, Kim BS, Kim E.
Yu C, et al. Among authors: kim bs.
Cell Death Differ. 2016 Nov 1;23(11):1873-1885. doi: 10.1038/cdd.2016.99. Epub 2016 Sep 23.
Cell Death Differ. 2016.
PMID: 27662363
Free PMC article.
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FAF1 mediates necrosis through JNK1-mediated mitochondrial dysfunction leading to retinal degeneration in the ganglion cell layer upon ischemic insult.
Yu C, Kim BS, Park M, Do YJ, Kong YY, Kim E.
Yu C, et al. Among authors: kim bs.
Cell Commun Signal. 2018 Sep 10;16(1):56. doi: 10.1186/s12964-018-0265-7.
Cell Commun Signal. 2018.
PMID: 30200976
Free PMC article.
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