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Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B. Hammond TR, et al. Among authors: walker aj. Immunity. 2019 Jan 15;50(1):253-271.e6. doi: 10.1016/j.immuni.2018.11.004. Epub 2018 Nov 21. Immunity. 2019. PMID: 30471926 Free PMC article.
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion.
Pinho-Ribeiro FA, Deng L, Neel DV, Erdogan O, Basu H, Yang D, Choi S, Walker AJ, Carneiro-Nascimento S, He K, Wu G, Stevens B, Doran KS, Levy D, Chiu IM. Pinho-Ribeiro FA, et al. Among authors: walker aj. Nature. 2023 Mar;615(7952):472-481. doi: 10.1038/s41586-023-05753-x. Epub 2023 Mar 1. Nature. 2023. PMID: 36859544 Free PMC article.
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Marsh SE, et al. Among authors: walker aj. Nat Neurosci. 2022 Mar;25(3):306-316. doi: 10.1038/s41593-022-01022-8. Epub 2022 Mar 8. Nat Neurosci. 2022. PMID: 35260865
A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis.
Mifflin L, Hu Z, Dufort C, Hession CC, Walker AJ, Niu K, Zhu H, Liu N, Liu JS, Levin JZ, Stevens B, Yuan J, Zou C. Mifflin L, et al. Among authors: walker aj. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2025102118. doi: 10.1073/pnas.2025102118. Proc Natl Acad Sci U S A. 2021. PMID: 33766915 Free PMC article.