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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
García-Prat L, Kaufmann KB, Schneiter F, Voisin V, Murison A, Chen J, Chan-Seng-Yue M, Gan OI, McLeod JL, Smith SA, Shoong MC, Parris D, Pan K, Zeng AGX, Krivdova G, Gupta K, Takayanagi SI, Wagenblast E, Wang W, Lupien M, Schroeder T, Xie SZ, Dick JE. García-Prat L, et al. Among authors: mcleod jl. Cell Stem Cell. 2021 Oct 7;28(10):1838-1850.e10. doi: 10.1016/j.stem.2021.07.003. Epub 2021 Aug 2. Cell Stem Cell. 2021. PMID: 34343492 Free article.
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.
Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, Kennedy JA, Schimmer AD, Schuh AC, Yee KW, McLeod JL, Doedens M, Medeiros JJ, Marke R, Kim HJ, Lee K, McPherson JD, Hudson TJ; HALT Pan-Leukemia Gene Panel Consortium; Brown AM, Yousif F, Trinh QM, Stein LD, Minden MD, Wang JC, Dick JE. Shlush LI, et al. Among authors: mcleod jl. Nature. 2014 Feb 20;506(7488):328-33. doi: 10.1038/nature13038. Epub 2014 Feb 12. Nature. 2014. PMID: 24522528 Free PMC article.
Mapping the cellular origin and early evolution of leukemia in Down syndrome.
Wagenblast E, Araújo J, Gan OI, Cutting SK, Murison A, Krivdova G, Azkanaz M, McLeod JL, Smith SA, Gratton BA, Marhon SA, Gabra M, Medeiros JJF, Manteghi S, Chen J, Chan-Seng-Yue M, Garcia-Prat L, Salmena L, De Carvalho DD, Abelson S, Abdelhaleem M, Chong K, Roifman M, Shannon P, Wang JCY, Hitzler JK, Chitayat D, Dick JE, Lechman ER. Wagenblast E, et al. Among authors: mcleod jl. Science. 2021 Jul 9;373(6551):eabf6202. doi: 10.1126/science.abf6202. Science. 2021. PMID: 34244384
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.
Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER. Krivdova G, et al. Among authors: mcleod jl. Cell Rep. 2022 Mar 8;38(10):110481. doi: 10.1016/j.celrep.2022.110481. Cell Rep. 2022. PMID: 35263585 Free article.
Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
Shlush LI, Mitchell A, Heisler L, Abelson S, Ng SWK, Trotman-Grant A, Medeiros JJF, Rao-Bhatia A, Jaciw-Zurakowsky I, Marke R, McLeod JL, Doedens M, Bader G, Voisin V, Xu C, McPherson JD, Hudson TJ, Wang JCY, Minden MD, Dick JE. Shlush LI, et al. Among authors: mcleod jl. Nature. 2017 Jul 6;547(7661):104-108. doi: 10.1038/nature22993. Epub 2017 Jun 28. Nature. 2017. PMID: 28658204