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BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells.
Moujalled D, Southon AG, Saleh E, Brinkmann K, Ke F, Iliopoulos M, Cross RS, Jenkins MR, Nhu D, Wang Z, Shi MX, Kluck RM, Lessene G, Grabow S, Bush AI, Strasser A. Moujalled D, et al. Among authors: shi mx. Cell Death Differ. 2022 Jul;29(7):1335-1348. doi: 10.1038/s41418-022-00977-2. Epub 2022 Mar 24. Cell Death Differ. 2022. PMID: 35332309 Free PMC article.
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Thijssen R, Diepstraten ST, Moujalled D, Chew E, Flensburg C, Shi MX, Dengler MA, Litalien V, MacRaild S, Chen M, Anstee NS, Reljić B, Gabriel SS, Djajawi TM, Riffkin CD, Aubrey BJ, Chang C, Tai L, Xu Z, Morley T, Pomilio G, Bruedigam C, Kallies A, Stroud DA, Bajel A, Kluck RM, Lane SW, Schoumacher M, Banquet S, Majewski IJ, Strasser A, Roberts AW, Huang DCS, Brown FC, Kelly GL, Wei AH. Thijssen R, et al. Among authors: shi mx. Blood. 2021 May 20;137(20):2721-2735. doi: 10.1182/blood.2020010167. Blood. 2021. PMID: 33824975 Free PMC article.