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Targeting lipophagy in macrophages improves repair in multiple sclerosis.
Haidar M, Loix M, Vanherle S, Dierckx T, Vangansewinkel T, Gervois P, Wolfs E, Lambrichts I, Bogie JFJ, Hendriks JJA. Haidar M, et al. Among authors: loix m. Autophagy. 2022 Nov;18(11):2697-2710. doi: 10.1080/15548627.2022.2047343. Epub 2022 Mar 14. Autophagy. 2022. PMID: 35282773 Free PMC article.
Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: loix m. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination.
Garcia Corrales AV, Verberk SGS, Haidar M, Grajchen E, Dehairs J, Vanherle S, Loix M, Weytjens T, Gervois P, Matsuzaka T, Lambrichts I, Swinnen JV, Bogie JFJ, Hendriks JJA. Garcia Corrales AV, et al. Among authors: loix m. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2301030120. doi: 10.1073/pnas.2301030120. Epub 2023 Sep 5. Proc Natl Acad Sci U S A. 2023. PMID: 37669365 Free PMC article.
Extracellular vesicle-associated cholesterol supports the regenerative functions of macrophages in the brain.
Vanherle S, Guns J, Loix M, Mingneau F, Dierckx T, Wouters F, Kuipers K, Vangansewinkel T, Wolfs E, Lins PP, Bronckaers A, Lambrichts I, Dehairs J, Swinnen JV, Verberk SGS, Haidar M, Hendriks JJA, Bogie JFJ. Vanherle S, et al. Among authors: loix m. J Extracell Vesicles. 2023 Dec;12(12):e12394. doi: 10.1002/jev2.12394. J Extracell Vesicles. 2023. PMID: 38124258 Free PMC article.
Lipophagy: a new player in CNS disorders.
Haidar M, Loix M, Bogie JFJ, Hendriks JJA. Haidar M, et al. Among authors: loix m. Trends Endocrinol Metab. 2021 Nov;32(11):941-951. doi: 10.1016/j.tem.2021.08.010. Epub 2021 Sep 21. Trends Endocrinol Metab. 2021. PMID: 34561114 Review.
Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages.
van Wouw SAE, van den Berg M, El Ouraoui M, Meurs A, Kingma J, Ottenhoff R, Loix M, Hoeksema MA, Prange K, Pasterkamp G, Hendriks JJA, Bogie JFJ, van Klinken JB, Vaz FM, Jongejan A, de Winther MPJ, Zelcer N. van Wouw SAE, et al. Among authors: loix m. J Lipid Res. 2023 Feb;64(2):100325. doi: 10.1016/j.jlr.2022.100325. Epub 2022 Dec 31. J Lipid Res. 2023. PMID: 36592658 Free PMC article.
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