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2012 1
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2023 7
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FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M. Doll S, et al. Among authors: xavier da silva tn. Nature. 2019 Nov;575(7784):693-698. doi: 10.1038/s41586-019-1707-0. Epub 2019 Oct 21. Nature. 2019. PMID: 31634899
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.
Barayeu U, Schilling D, Eid M, Xavier da Silva TN, Schlicker L, Mitreska N, Zapp C, Gräter F, Miller AK, Kappl R, Schulze A, Friedmann Angeli JP, Dick TP. Barayeu U, et al. Among authors: xavier da silva tn. Nat Chem Biol. 2023 Jan;19(1):28-37. doi: 10.1038/s41589-022-01145-w. Epub 2022 Sep 15. Nat Chem Biol. 2023. PMID: 36109647 Free PMC article.
The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2.
Kreß JKC, Jessen C, Hufnagel A, Schmitz W, Xavier da Silva TN, Ferreira Dos Santos A, Mosteo L, Goding CR, Friedmann Angeli JP, Meierjohann S. Kreß JKC, et al. Among authors: xavier da silva tn. Cell Rep. 2023 Jul 25;42(7):112724. doi: 10.1016/j.celrep.2023.112724. Epub 2023 Jul 4. Cell Rep. 2023. PMID: 37410595 Free article.
GPX4: old lessons, new features.
Nishida Xavier da Silva T, Friedmann Angeli JP, Ingold I. Nishida Xavier da Silva T, et al. Biochem Soc Trans. 2022 Jun 30;50(3):1205-1213. doi: 10.1042/BST20220682. Biochem Soc Trans. 2022. PMID: 35758268 Review.
CD8+ T cells PUF(A)ing the flames of cancer ferroptotic cell death.
Friedmann Angeli JP, Xavier da Silva TN, Schilling B. Friedmann Angeli JP, et al. Among authors: xavier da silva tn. Cancer Cell. 2022 Apr 11;40(4):346-348. doi: 10.1016/j.ccell.2022.03.003. Epub 2022 Mar 24. Cancer Cell. 2022. PMID: 35334204 Free article.
Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.
Nakamura T, Mishima E, Yamada N, Mourão ASD, Trümbach D, Doll S, Wanninger J, Lytton E, Sennhenn P, Nishida Xavier da Silva T, Angeli JPF, Sattler M, Proneth B, Conrad M. Nakamura T, et al. Among authors: nishida xavier da silva t. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815. doi: 10.1038/s41594-023-01136-y. Epub 2023 Nov 13. Nat Struct Mol Biol. 2023. PMID: 37957306 Free PMC article.
Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent manner.
Meinert M, Jessen C, Hufnagel A, Kreß JKC, Burnworth M, Däubler T, Gallasch T, Xavier da Silva TN, Dos Santos AF, Ade CP, Schmitz W, Kneitz S, Friedmann Angeli JP, Meierjohann S. Meinert M, et al. Among authors: xavier da silva tn. Redox Biol. 2024 Apr;70:103011. doi: 10.1016/j.redox.2023.103011. Epub 2023 Dec 27. Redox Biol. 2024. PMID: 38219574 Free PMC article.
13 results