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Year Number of Results
2006 1
2007 2
2009 2
2010 1
2011 2
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2013 1
2015 2
2022 3
2023 9
2024 4

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Page 1
AI-powered therapeutic target discovery.
Pun FW, Ozerov IV, Zhavoronkov A. Pun FW, et al. Trends Pharmacol Sci. 2023 Sep;44(9):561-572. doi: 10.1016/j.tips.2023.06.010. Epub 2023 Jul 19. Trends Pharmacol Sci. 2023. PMID: 37479540 Free article. Review.
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models.
Ren F, Aliper A, Chen J, Zhao H, Rao S, Kuppe C, Ozerov IV, Zhang M, Witte K, Kruse C, Aladinskiy V, Ivanenkov Y, Polykovskiy D, Fu Y, Babin E, Qiao J, Liang X, Mou Z, Wang H, Pun FW, Ayuso PT, Veviorskiy A, Song D, Liu S, Zhang B, Naumov V, Ding X, Kukharenko A, Izumchenko E, Zhavoronkov A. Ren F, et al. Among authors: pun fw. Nat Biotechnol. 2024 Mar 8. doi: 10.1038/s41587-024-02143-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38459338
Leveraging AI to identify dual-purpose aging and disease targets.
Leung GHD, Wong CW, Pun FW, Aliper A, Ren F, Zhavoronkov A. Leung GHD, et al. Among authors: pun fw. Expert Opin Ther Targets. 2023 Dec 1:1-4. doi: 10.1080/14728222.2023.2288270. Online ahead of print. Expert Opin Ther Targets. 2023. PMID: 38038952 No abstract available.
TNIK's emerging role in cancer, metabolism, and age-related diseases.
Ewald CY, Pulous FE, Lok SWY, Pun FW, Aliper A, Ren F, Zhavoronkov A. Ewald CY, et al. Among authors: pun fw. Trends Pharmacol Sci. 2024 May 21:S0165-6147(24)00090-7. doi: 10.1016/j.tips.2024.04.010. Online ahead of print. Trends Pharmacol Sci. 2024. PMID: 38777670 Free article. Review.
AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor.
Ren F, Ding X, Zheng M, Korzinkin M, Cai X, Zhu W, Mantsyzov A, Aliper A, Aladinskiy V, Cao Z, Kong S, Long X, Man Liu BH, Liu Y, Naumov V, Shneyderman A, Ozerov IV, Wang J, Pun FW, Polykovskiy DA, Sun C, Levitt M, Aspuru-Guzik A, Zhavoronkov A. Ren F, et al. Among authors: pun fw. Chem Sci. 2023 Jan 10;14(6):1443-1452. doi: 10.1039/d2sc05709c. eCollection 2023 Feb 8. Chem Sci. 2023. PMID: 36794205 Free PMC article.
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform.
Olsen A, Harpaz Z, Ren C, Shneyderman A, Veviorskiy A, Dralkina M, Konnov S, Shcheglova O, Pun FW, Leung GHD, Leung HW, Ozerov IV, Aliper A, Korzinkin M, Zhavoronkov A. Olsen A, et al. Among authors: pun fw. Aging (Albany NY). 2023 Apr 26;15(8):2863-2876. doi: 10.18632/aging.204678. Epub 2023 Apr 26. Aging (Albany NY). 2023. PMID: 37100462 Free PMC article.
25 results