Genetic variants of calcium and vitamin D metabolism in kidney stone disease.
Howles SA, Wiberg A, Goldsworthy M, Bayliss AL, Gluck AK, Ng M, Grout E, Tanikawa C, Kamatani Y, Terao C, Takahashi A, Kubo M, Matsuda K, Thakker RV, Turney BW, Furniss D.
Howles SA, et al. Among authors: furniss d.
Nat Commun. 2019 Nov 15;10(1):5175. doi: 10.1038/s41467-019-13145-x.
Nat Commun. 2019.
PMID: 31729369
Free PMC article.
We present genome-wide association studies in British and Japanese populations and a trans-ethnic meta-analysis that include 12,123 cases and 417,378 controls, and identify 20 nephrolithiasis-associated loci, seven of which are previously unreported. A CYP24A1 locus is predicted …
We present genome-wide association studies in British and Japanese populations and a trans-ethnic meta-analysis that include 12,123 cases an …