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C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo.
Nat Neurosci. 2019 Jun;22(6):851-862. doi: 10.1038/s41593-019-0397-0. Epub 2019 May 13.
Nat Neurosci. 2019.
PMID: 31086314
Free PMC article.
Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia.
Phillips HL, Dai H, Choi SY, Jansen-West K, Zajicek AS, Daly L, Petrucelli L, Gao FB, Yao WD.
Phillips HL, et al.
Neuron. 2023 Mar 15;111(6):797-806.e6. doi: 10.1016/j.neuron.2022.12.027. Epub 2023 Jan 12.
Neuron. 2023.
PMID: 36638803
Free PMC article.
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Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling.
Zajicek AS, Ruan H, Dai H, Skolfield MC, Phillips HL, Burnette WJ, Javidfar B, Sun SC, Akbarian S, Yao WD.
Zajicek AS, et al. Among authors: phillips hl.
Mol Psychiatry. 2022 May;27(5):2414-2424. doi: 10.1038/s41380-022-01571-1. Epub 2022 Apr 21.
Mol Psychiatry. 2022.
PMID: 35449295
Free PMC article.
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