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A phase 1b study of glasdegib + azacitidine in patients with untreated acute myeloid leukemia and higher-risk myelodysplastic syndromes.
Ann Hematol. 2022 Aug;101(8):1689-1701. doi: 10.1007/s00277-022-04853-4. Epub 2022 Apr 30.
Ann Hematol. 2022.
PMID: 35488900
Clinical Trial.
Single-cell quantitative HER2 measurement identifies heterogeneity and distinct subgroups within traditionally defined HER2-positive patients.
Onsum MD, Geretti E, Paragas V, Kudla AJ, Moulis SP, Luus L, Wickham TJ, McDonagh CF, MacBeath G, Hendriks BS.
Onsum MD, et al. Among authors: kudla aj.
Am J Pathol. 2013 Nov;183(5):1446-1460. doi: 10.1016/j.ajpath.2013.07.015. Epub 2013 Sep 11.
Am J Pathol. 2013.
PMID: 24035511
Free article.
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Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.
Schoeberl B, Pace EA, Fitzgerald JB, Harms BD, Xu L, Nie L, Linggi B, Kalra A, Paragas V, Bukhalid R, Grantcharova V, Kohli N, West KA, Leszczyniecka M, Feldhaus MJ, Kudla AJ, Nielsen UB.
Schoeberl B, et al. Among authors: kudla aj.
Sci Signal. 2009 Jun 30;2(77):ra31. doi: 10.1126/scisignal.2000352.
Sci Signal. 2009.
PMID: 19567914
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Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.
McDonagh CF, Huhalov A, Harms BD, Adams S, Paragas V, Oyama S, Zhang B, Luus L, Overland R, Nguyen S, Gu J, Kohli N, Wallace M, Feldhaus MJ, Kudla AJ, Schoeberl B, Nielsen UB.
McDonagh CF, et al. Among authors: kudla aj.
Mol Cancer Ther. 2012 Mar;11(3):582-93. doi: 10.1158/1535-7163.MCT-11-0820. Epub 2012 Jan 16.
Mol Cancer Ther. 2012.
PMID: 22248472
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