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Page 1
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH. Eschweiler S, et al. Among authors: dicker m. Nature. 2022 May;605(7911):741-746. doi: 10.1038/s41586-022-04685-2. Epub 2022 May 4. Nature. 2022. PMID: 35508656 Free PMC article. Clinical Trial.
CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways.
Dicker M, Li Y, Giles DA, Verstichel G, Castelan VC, Ascui-Gac G, Chou TF, Perez-Jeldres T, Cheroutre H, Kronenberg M. Dicker M, et al. Front Immunol. 2022 Oct 28;13:1034648. doi: 10.3389/fimmu.2022.1034648. eCollection 2022. Front Immunol. 2022. PMID: 36389671 Free PMC article.
Using glyco-engineering to produce therapeutic proteins.
Dicker M, Strasser R. Dicker M, et al. Expert Opin Biol Ther. 2015;15(10):1501-16. doi: 10.1517/14712598.2015.1069271. Epub 2015 Jul 14. Expert Opin Biol Ther. 2015. PMID: 26175280 Free PMC article. Review.
Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils.
Riffelmacher T, Giles DA, Zahner S, Dicker M, Andreyev AY, McArdle S, Perez-Jeldres T, van der Gracht E, Murray MP, Hartmann N, Tumanov AV, Kronenberg M. Riffelmacher T, et al. Among authors: dicker m. Mucosal Immunol. 2021 May;14(3):679-690. doi: 10.1038/s41385-021-00378-7. Epub 2021 Feb 10. Mucosal Immunol. 2021. PMID: 33568785 Free PMC article.
11 results