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Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma.
Chen Z, Soni N, Pinero G, Giotti B, Eddins DJ, Lindblad KE, Ross JL, Puigdelloses Vallcorba M, Joshi T, Angione A, Thomason W, Keane A, Tsankova NM, Gutmann DH, Lira SA, Lujambio A, Ghosn EEB, Tsankov AM, Hambardzumyan D. Chen Z, et al. Among authors: angione a. Nat Commun. 2023 Apr 3;14(1):1839. doi: 10.1038/s41467-023-37361-8. Nat Commun. 2023. PMID: 37012245 Free PMC article.
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Chen Z, Giotti B, Kaluzova M, Vallcorba MP, Rawat K, Price G, Herting CJ, Pinero G, Cristea S, Ross JL, Ackley J, Maximov V, Szulzewsky F, Thomason W, Marquez-Ropero M, Angione A, Nichols N, Tsankova NM, Michor F, Shayakhmetov DM, Gutmann DH, Tsankov AM, Hambardzumyan D. Chen Z, et al. Among authors: angione a. J Clin Invest. 2023 Nov 15;133(22):e163802. doi: 10.1172/JCI163802. J Clin Invest. 2023. PMID: 37733448 Free PMC article.
A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell-of-origin dependent effects of H3K27M.
Tomita Y, Shimazu Y, Somasundaram A, Tanaka Y, Takata N, Ishi Y, Gadd S, Hashizume R, Angione A, Pinero G, Hambardzumyan D, Brat DJ, Hoeman CM, Becher OJ. Tomita Y, et al. Among authors: angione a. Glia. 2022 Sep;70(9):1681-1698. doi: 10.1002/glia.24189. Epub 2022 May 7. Glia. 2022. PMID: 35524725 Free PMC article.
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis.
Rao A, Zhang X, Cillo AR, Sussman JH, Sandlesh P, Tarbay AC, Mallela AN, Cardello C, Krueger K, Xu J, Li A, Xu J, Patterson J, Akca E, Angione A, Jaman E, Kim WJ, Allen J, Venketeswaran A, Zinn PO, Parise R, Beumer J, Duensing A, Holland EC, Ferris R, Bagley SJ, Bruno TC, Vignali DAA, Agnihotri S, Amankulor NM. Rao A, et al. Among authors: angione a. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588752. doi: 10.1101/2024.04.09.588752. bioRxiv. 2024. PMID: 38645178 Free PMC article. Preprint.