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Page 1
IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype.
Domínguez-Zorita S, Romero-Carramiñana I, Santacatterina F, Esparza-Moltó PB, Simó C, Del-Arco A, Núñez de Arenas C, Saiz J, Barbas C, Cuezva JM. Domínguez-Zorita S, et al. Among authors: nunez de arenas c. Cell Death Dis. 2023 Jul 12;14(7):413. doi: 10.1038/s41419-023-05957-z. Cell Death Dis. 2023. PMID: 37433784 Free PMC article.
Exacerbated response to oxidative stress in the Retinitis Pigmentosa CerklKD/KO mouse model triggers retinal degeneration pathways upon acute light stress.
García-Arroyo R, Domènech EB, Herrera-Úbeda C, Asensi MA, Núñez de Arenas C, Cuezva JM, Garcia-Fernàndez J, Pallardó FV, Mirra S, Marfany G. García-Arroyo R, et al. Among authors: nunez de arenas c. Redox Biol. 2023 Oct;66:102862. doi: 10.1016/j.redox.2023.102862. Epub 2023 Aug 28. Redox Biol. 2023. PMID: 37660443 Free PMC article.
Effective therapeutic strategies in a preclinical mouse model of Charcot-Marie-Tooth disease.
Nuevo-Tapioles C, Santacatterina F, Sánchez-Garrido B, de Arenas CN, Robledo-Bérgamo A, Martínez-Valero P, Cantarero L, Pardo B, Hoenicka J, Murphy MP, Satrústegui J, Palau F, Cuezva JM. Nuevo-Tapioles C, et al. Among authors: de arenas cn. Hum Mol Genet. 2021 Nov 30;30(24):2441-2455. doi: 10.1093/hmg/ddab207. Hum Mol Genet. 2021. PMID: 34274972 Free PMC article.
Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates.
Sánchez-González C, Herrero Martín JC, Salegi Ansa B, Núñez de Arenas C, Stančič B, Pereira MP, Contreras L, Cuezva JM, Formentini L. Sánchez-González C, et al. Among authors: nunez de arenas c. Cell Death Dis. 2022 Jun 22;13(6):561. doi: 10.1038/s41419-022-05016-z. Cell Death Dis. 2022. PMID: 35732639 Free PMC article.
Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition.
Esparza-Moltó PB, Romero-Carramiñana I, Núñez de Arenas C, Pereira MP, Blanco N, Pardo B, Bates GR, Sánchez-Castillo C, Artuch R, Murphy MP, Esteban JA, Cuezva JM. Esparza-Moltó PB, et al. Among authors: nunez de arenas c. PLoS Biol. 2021 May 13;19(5):e3001252. doi: 10.1371/journal.pbio.3001252. eCollection 2021 May. PLoS Biol. 2021. PMID: 33983919 Free PMC article.
Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy.
Torresano L, Santacatterina F, Domínguez-Zorita S, Nuevo-Tapioles C, Núñez-Salgado A, Esparza-Moltó PB, González-Llorente L, Romero-Carramiñana I, Núñez de Arenas C, Sánchez-Garrido B, Nájera L, Salas C, Provencio M, Cuezva JM. Torresano L, et al. Among authors: nunez de arenas c. Oncogenesis. 2022 May 9;11(1):24. doi: 10.1038/s41389-022-00400-y. Oncogenesis. 2022. PMID: 35534478 Free PMC article.
Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state.
Santacatterina F, Sánchez-Cenizo L, Formentini L, Mobasher MA, Casas E, Rueda CB, Martínez-Reyes I, Núñez de Arenas C, García-Bermúdez J, Zapata JM, Sánchez-Aragó M, Satrústegui J, Valverde ÁM, Cuezva JM. Santacatterina F, et al. Among authors: nunez de arenas c. Oncotarget. 2016 Jan 5;7(1):490-508. doi: 10.18632/oncotarget.6357. Oncotarget. 2016. PMID: 26595676 Free PMC article.
11 results