Gregory B Craven[Author] - Search Results

Year	Number of Results
2018	3
2019	1
2020	2
2021	2
2022	4
2023	2
2024	0

1

Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.

Chen Y, Craven GB, Kamber RA, Cuesta A, Zhersh S, Moroz YS, Bassik MC, Taunton J. Chen Y, et al. Among authors: craven gb. Nat Chem. 2023 Nov;15(11):1616-1625. doi: 10.1038/s41557-023-01281-3. Epub 2023 Jul 17. Nat Chem. 2023. PMID: 37460812

2

Signal peptide mimicry primes Sec61 for client-selective inhibition.

Rehan S, Tranter D, Sharp PP, Craven GB, Lowe E, Anderl JL, Muchamuel T, Abrishami V, Kuivanen S, Wenzell NA, Jennings A, Kalyanaraman C, Strandin T, Javanainen M, Vapalahti O, Jacobson MP, McMinn D, Kirk CJ, Huiskonen JT, Taunton J, Paavilainen VO. Rehan S, et al. Among authors: craven gb. Nat Chem Biol. 2023 Sep;19(9):1054-1062. doi: 10.1038/s41589-023-01326-1. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169961 Free PMC article.

3

Reversible lysine-targeted probes reveal residence time-based kinase selectivity.

Yang T, Cuesta A, Wan X, Craven GB, Hirakawa B, Khamphavong P, May JR, Kath JC, Lapek JD Jr, Niessen S, Burlingame AL, Carelli JD, Taunton J. Yang T, et al. Among authors: craven gb. Nat Chem Biol. 2022 Sep;18(9):934-941. doi: 10.1038/s41589-022-01019-1. Epub 2022 May 19. Nat Chem Biol. 2022. PMID: 35590003 Free PMC article.

4

Synthesis and Configurational Assignment of Vinyl Sulfoximines and Sulfonimidamides.

Craven GB, Briggs EL, Zammit CM, McDermott A, Greed S, Affron DP, Leinfellner C, Cudmore HR, Tweedy RR, Luisi R, Bull JA, Armstrong A. Craven GB, et al. J Org Chem. 2021 Jun 4;86(11):7403-7424. doi: 10.1021/acs.joc.1c00373. Epub 2021 May 18. J Org Chem. 2021. PMID: 34003635

5

High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery.

Craven GB, Affron DP, Allen CE, Matthies S, Greener JG, Morgan RML, Tate EW, Armstrong A, Mann DJ. Craven GB, et al. Angew Chem Int Ed Engl. 2018 May 4;57(19):5257-5261. doi: 10.1002/anie.201711825. Epub 2018 Mar 26. Angew Chem Int Ed Engl. 2018. PMID: 29480525 Free PMC article.

6

Quantitative Irreversible Tethering (qIT) for Target-directed Covalent Fragment Screening.

Craven GB, Armstrong A, Mann DJ. Craven GB, et al. Bio Protoc. 2020 Dec 20;10(24):e3855. doi: 10.21769/BioProtoc.3855. eCollection 2020 Dec 20. Bio Protoc. 2020. PMID: 33659502 Free PMC article.

7

Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.

Qin B, Craven GB, Hou P, Chesti J, Lu X, Child ES, Morgan RML, Niu W, Zhao L, Armstrong A, Mann DJ, Cui S. Qin B, et al. Among authors: craven gb. Acta Pharm Sin B. 2022 Oct;12(10):3924-3933. doi: 10.1016/j.apsb.2022.06.002. Epub 2022 Jun 9. Acta Pharm Sin B. 2022. PMID: 35702321 Free PMC article.

8

Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A.

Liu Y, De Castro Ribeiro O, Haapanen O, Craven GB, Sharma V, Muench SP, Goldman A. Liu Y, et al. Among authors: craven gb. J Biol Chem. 2022 Oct;298(10):102380. doi: 10.1016/j.jbc.2022.102380. Epub 2022 Aug 17. J Biol Chem. 2022. PMID: 35985422 Free PMC article.

9

Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.

Jamshidiha M, Lanyon-Hogg T, Sutherell CL, Craven GB, Tersa M, De Vita E, Brustur D, Pérez-Dorado I, Hassan S, Petracca R, Morgan RM, Sanz-Hernández M, Norman JC, Armstrong A, Mann DJ, Cota E, Tate EW. Jamshidiha M, et al. Among authors: craven gb. RSC Med Chem. 2021 Dec 16;13(2):150-155. doi: 10.1039/d1md00225b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308027 Free PMC article.

10

Multiparameter Kinetic Analysis for Covalent Fragment Optimization by Using Quantitative Irreversible Tethering (qIT).

Craven GB, Affron DP, Kösel T, Wong TLM, Jukes ZH, Liu CT, Morgan RML, Armstrong A, Mann DJ. Craven GB, et al. Chembiochem. 2020 Dec 1;21(23):3417-3422. doi: 10.1002/cbic.202000457. Epub 2020 Aug 7. Chembiochem. 2020. PMID: 32659037 Free PMC article.

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